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MIRAGE
Prostaglandin G/H synthase 2

Summary
UniProt ID
Q05769
Gene Symbol
  • Cox-2
  • Cox2
  • Pghs-b
  • Ptgs2
  • Tis10
Gene ID
19225
Organism
Mus musculus (house mouse)
GlyConnect
GlyGen
Q05769
PubChem
Q05769
SwissLipids
Re-Glyco
Q05769
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Dioxygenase
  • Direct protein sequencing
  • Disulfide bond
  • Glycoprotein
  • Heme
  • Membrane
  • Microsome
  • Nucleus
  • Peroxidase
  • Prostaglandin biosynthesis
  • Reference proteome
  • S-nitrosylation
  • Signal
Gene Ontology (GO)
Displaying all 7 entries
GO Term
cytoplasm
protein-containing complex
neuron projection
endoplasmic reticulum membrane
nuclear inner membrane
nuclear outer membrane
caveola
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Site Annotations
Displaying 1 entry
Position Description
592 Not glycosylated
Annotation information from UniProt.
Sequence
MLFRAVLLCAALGLSQAANPCCSNPCQNRGECMSTGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPNTVHYILTHFKGVWNIVNNIPFLRSLIMKYVLTSRSYLIDSPPTYNVHYGYKSWEAFSNLSYYTRALPPVADDCPTPMGVKGNKELPDSKEVLEKVLLRREFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPGFTRGLGHGVDLNHIYGETLDRQHKLRLFKDGKLKYQVIGGEVYPPTVKDTQVEMIYPPHIPENLQFAVGQEVFGLVPGLMMYATIWLREHNRVCDILKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIASEFNTLYHWHPLLPDTFNIEDQEYSFKQFLYNNSILLEHGLTQFVESFTRQIAGRVAGGRNVPIAVQAVAKASIDQSREMKYQSLNEYRKRFSLKPYTSFEELTGEKEMAAELKALYSDIDVMELYPALLVEKPRPDAIFGETMVELGAPFSLKGLMGNPICSPQYWKPSTFGGEVGFKIINTASIQSLICNNVKGCPFTSFNVQDPQPTKTATINASASHSRLDDINPTVLIKRRSTEL
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 4 entries
Position Description PubMed ID GlyTouCan ID Source
53 N-linked (GlcNAc...) asparagine
130 N-linked (GlcNAc...) asparagine
396 N-linked (GlcNAc...) asparagine
580 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 7 entries
Pathway Name Organism
Biosynthesis of DHA-derived SPMs Mus musculus
Biosynthesis of DPAn-3 SPMs Mus musculus
Biosynthesis of EPA-derived SPMs Mus musculus
Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives Mus musculus
Nicotinamide salvaging Mus musculus
Synthesis of 15-eicosatetraenoic acid derivatives Mus musculus
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) Mus musculus
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025