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Fibroblast growth factor receptor homolog 1
Summary
- UniProt ID
- Q07407
- Gene Symbol
- CG7223 FR1 Tk1 htl
- Gene ID
- 42160
- Organism
- Drosophila melanogaster (fruit fly)
Annotation
- Keyword
- ATP-binding Developmental protein Disulfide bond Glycoprotein Immunoglobulin domain Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane helix Tyrosine-protein kinase
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| mesoderm migration involved in gastrulation | ||
| visceral muscle development | ||
| larval visceral muscle development | ||
| somatic muscle development | ||
| mesodermal cell migration |
GO Hierarchy
biological process
cellular process [inference]
developmental process [inference]
biological regulation [inference]
regulation of biological process [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| signaling receptor complex | ||
| postsynapse of neuromuscular junction |
| GO Term | Evidence Code | Reference |
|---|---|---|
| protein tyrosine kinase activity | ||
| protein tyrosine kinase activity | ||
| transmembrane receptor protein tyrosine kinase activity | ||
| transmembrane receptor protein tyrosine kinase activity | ||
| transmembrane receptor protein tyrosine kinase activity |
GO Hierarchy
Sequence
MAAAWSWRASHSTITMTSGSLVVLFLLLSIWQPAVQVEGRRQMANSQEMIKDHLGARSQNKTPAITNNANQSSTSSADLDDGAADDDDNKADLPVNVSSKPYWRNPKKMSFLQTRPSGSLLTLNCHALGNPEPNITWYRNGTVDWTRGYGSLKRNRWTLTMEDLVPGDCGNYTCKVCNSLGCIRHDTQVIVSDRVNHKPILMTGPLNLTLVVNSTGSMHCKYLSDLTSKKAWIFVPCHGMTNCSNNRSIIAEDKDQLDFVNVRMEQEGWYTCVESNSLGQSNSTAYLRVVRSLHVLEAGVASGSLHSTSFVYIFVFGGLIFIFMTTLFVFYAIRKMKHEKVLKQRIETVHQWTKKVIIFKPEGGGDSSGSMDTMIMPVVRIQKQRTTVLQNGNEPAPFNEYEFPLDSNWELPRSHLVLGATLGEGAFGRVVMAEVNNAIVAVKMVKEGHTDDDIASLVREMEVMKIIGRHINIINLLGCCSQNGPLYVIVEYAPHGNLKDFLYKNRPFGRDQDRDSSQPPPSPPAHVITEKDLIKFAHQIARGMDYLASRRCIHRDLAARNVLVSDDYVLKIADFGLARDIQSTDYYRKNTNGRLPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVEYMDKLLQTKEDYLDVDIANLDTPPSTSDEEEDETDNLQKWCNY
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 70 |
|
|
||
| 96 |
|
|
||
| 134 |
|
|
||
| 140 |
|
|
||
| 171 |
|
|
||
| 207 |
|
|
||
| 213 |
|
|
||
| 242 |
|
|
||
| 246 |
|
|
||
| 282 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| FGFR2b ligand binding and activation | Drosophila melanogaster |
| FGFR2c ligand binding and activation | Drosophila melanogaster |
| FGFR3b ligand binding and activation | Drosophila melanogaster |
| FGFR3c ligand binding and activation | Drosophila melanogaster |
| FGFR4 ligand binding and activation | Drosophila melanogaster |
| FRS-mediated FGFR2 signaling | Drosophila melanogaster |
| FRS-mediated FGFR3 signaling | Drosophila melanogaster |
| FRS-mediated FGFR4 signaling | Drosophila melanogaster |
| Negative regulation of FGFR2 signaling | Drosophila melanogaster |
| Negative regulation of FGFR3 signaling | Drosophila melanogaster |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3070 | high grade glioma |
