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Serine protease inhibitor 77Ba

Summary

UniProt ID: Q0E8C8
Gene Symbol: CG6680 Spn77Ba
Gene ID: 40234
Organism: Drosophila melanogaster (fruit fly)

External Links

Re-Glyco: Q0E8C8

Annotation

Keyword: Glycoprotein Melanin biosynthesis Reference proteome Secreted Serine protease inhibitor Signal

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	Reference
negative regulation of melanization defense response	IMP	PMID
melanin biosynthetic process
negative regulation of proteolysis	ISM	PMID
regulation of immune response	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

secondary metabolite biosynthetic process [inference]

melanin biosynthetic process

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

phenol-containing compound metabolic process [inference]

melanin metabolic process [inference]

melanin biosynthetic process

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

secondary metabolic process [inference]

melanin metabolic process [inference]

melanin biosynthetic process

secondary metabolite biosynthetic process [inference]

melanin biosynthetic process

pigment metabolic process [inference]

melanin metabolic process [inference]

melanin biosynthetic process

pigment biosynthetic process [inference]

melanin biosynthetic process

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of immune response

regulation of innate immune response [inference]

regulation of melanization defense response [inference]

negative regulation of melanization defense response

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis

negative regulation of melanization defense response

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of defense response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of innate immune response [inference]

regulation of melanization defense response [inference]

negative regulation of melanization defense response

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of innate immune response [inference]

regulation of melanization defense response [inference]

negative regulation of melanization defense response

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of defense response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of immune response

regulation of innate immune response [inference]

regulation of melanization defense response [inference]

negative regulation of melanization defense response

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of innate immune response [inference]

regulation of melanization defense response [inference]

negative regulation of melanization defense response

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of cellular process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis

negative regulation of melanization defense response

regulation of secondary metabolic process [inference]

regulation of melanization defense response [inference]

negative regulation of melanization defense response

regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis

negative regulation of melanization defense response

Displaying 1 entry
GO Term	Evidence Code	Reference
obsolete extracellular space

GO Hierarchy

cellular component

Displaying 1 entry
GO Term	Evidence Code	Reference
serine-type endopeptidase inhibitor activity	IEA	GO_REF

GO Hierarchy

molecular function

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

peptidase regulator activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

endopeptidase regulator activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MGKIADCLMLWIPLLLGAIFLCSADPQNNQAPLQLSVGNPLTAFTAPTAFQSGVSHIQSMRSNFDTDVLVSISQGVQDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRINVEDEKLRGAYKVWSSFLNITTSTIEVATLQAIYTGKGYPIKNNYRDAIQNYNVQPMEVDFYSPDSVIQINEDTNRTTRGLIPYTILPQDVYGAKMFLLSSLYFKGQWKFPFNKTLTREEPFFSESGEVIGKIPMMVQEANFAYVSNVEGLDGYVLELPYGTQDRLAMIVVLPKRGFKLNDVANNLKALGLRPILQRLAAFRNRASEDNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTANLDRMSSGLFAKLVVHSTKIIVDEQGTTAGAVTEAALANKATPPKFLLNRPFQYMIVEKATGLLLFAGQVRNPKAA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	Source
149	N-linked (GlcNAc...) asparagine	UniProt
205	N-linked (GlcNAc...) asparagine	UniProt
243	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 8** entries
Pathway Name	Organism
CASP4 inflammasome assembly	Drosophila melanogaster
Collagen biosynthesis and modifying enzymes	Drosophila melanogaster
Neutrophil degranulation	Drosophila melanogaster
Platelet degranulation	Drosophila melanogaster
Post-translational protein phosphorylation	Drosophila melanogaster
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	Drosophila melanogaster
Regulation of FXIIa and plasma kallikrein activity	Drosophila melanogaster
Regulation of IGF Activity by IGFBP	Drosophila melanogaster