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Serpin 77Ba

Summary

Gene Symbol

Spn77Ba

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

40234

PubChem

40234

Alliance of Genome Resources

FB:FBgn0262057

Annotation

Keyword

Glycoprotein
Melanin biosynthesis
Reference proteome
Secreted
Serine protease inhibitor
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q0E8C8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
negative regulation of peptidase activity
negative regulation of melanization defense response	IMP	18854145
melanin biosynthetic process
negative regulation of proteolysis	ISM	19849829
regulation of immune response	IBA

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

aromatic compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

secondary metabolite biosynthetic process [inference]

melanin biosynthetic process

organic substance biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

organic hydroxy compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

secondary metabolic process [inference]

melanin metabolic process [inference]

melanin biosynthetic process

secondary metabolite biosynthetic process [inference]

melanin biosynthetic process

pigment metabolic process [inference]

melanin metabolic process [inference]

melanin biosynthetic process

pigment biosynthetic process [inference]

melanin biosynthetic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

melanin metabolic process [inference]

melanin biosynthetic process

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

aromatic compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

cellular biosynthetic process [inference]

aromatic compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

organic substance metabolic process [inference]

organic cyclic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

melanin metabolic process [inference]

melanin biosynthetic process

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

organic cyclic compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

organic substance biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

organic hydroxy compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

organic hydroxy compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

melanin metabolic process [inference]

melanin biosynthetic process

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

organic hydroxy compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

melanin metabolic process [inference]

melanin biosynthetic process

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

aromatic compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

cellular biosynthetic process [inference]

aromatic compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of immune response

regulation of innate immune response [inference]

regulation of melanization defense response [inference]

negative regulation of melanization defense response

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis

negative regulation of peptidase activity

negative regulation of cellular metabolic process [inference]

negative regulation of melanization defense response

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis

negative regulation of peptidase activity

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of melanization defense response

regulation of melanization defense response [inference]

negative regulation of melanization defense response

regulation of secondary metabolic process [inference]

regulation of melanization defense response [inference]

negative regulation of melanization defense response

regulation of nitrogen compound metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis

negative regulation of peptidase activity

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis

negative regulation of peptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis

negative regulation of peptidase activity

regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis

negative regulation of peptidase activity

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis

negative regulation of peptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis

negative regulation of peptidase activity

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis

negative regulation of peptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis

negative regulation of peptidase activity

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis

negative regulation of peptidase activity

negative regulation of cellular metabolic process [inference]

negative regulation of melanization defense response

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis

negative regulation of peptidase activity

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of melanization defense response

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of defense response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of innate immune response [inference]

regulation of melanization defense response [inference]

negative regulation of melanization defense response

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of innate immune response [inference]

regulation of melanization defense response [inference]

negative regulation of melanization defense response

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of defense response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of immune response

regulation of innate immune response [inference]

regulation of melanization defense response [inference]

negative regulation of melanization defense response

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of innate immune response [inference]

regulation of melanization defense response [inference]

negative regulation of melanization defense response

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of melanization defense response

regulation of melanization defense response [inference]

negative regulation of melanization defense response

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of melanization defense response

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity

regulation of hydrolase activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity

Displaying **all 3** entries
GO Term	Evidence Code	PMID
extracellular space	IDA	18854145
extracellular space	IBA
extracellular space	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

Displaying 1 entry
GO Term	Evidence Code	PMID
serine-type endopeptidase inhibitor activity	IEA

GO Hierarchy

molecular function

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

peptidase regulator activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

endopeptidase regulator activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Serine Protease inhibitor

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
serine-type endopeptidase inhibitor activity

Displaying **all 6** entries
InterPro
Serpin domain
Serpin family
Serpin superfamily, domain 1
Serpin superfamily, domain 2
Serpin superfamily
Serpin, conserved site

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
membrane	FB:FBrf0231198
extracellular space	PMID:18854145

Ortholog

Displaying **all 9** entries
Species	Gene ID	Alliance of Genome Resources
Danio rerio	183	ZFIN:ZDB-GENE-030131-1205
Danio rerio	871	ZFIN:ZDB-GENE-080219-21
Danio rerio	12406	ZFIN:ZDB-GENE-990415-93
Danio rerio	24179	ZFIN:ZDB-GENE-030131-1205
Danio rerio	29345	ZFIN:ZDB-GENE-990415-93
Xenopus tropicalis	40234	Xenbase:XB-GENE-983018
Xenopus tropicalis	51156	Xenbase:XB-GENE-983018
Xenopus tropicalis	171154	Xenbase:XB-GENE-983018
Xenopus tropicalis	217847	Xenbase:XB-GENE-983018

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements