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MIRAGE
Calcium/calmodulin-dependent protein kinase type II subunit beta
Summary
- UniProt ID
- Q13554
- Gene Symbol
- CAMK2B CAM2 CAMK2 CAMKB
- Gene ID
- 816
- Organism
- Homo sapiens (human)
Annotation
- Keyword
- 3D-structure ATP-binding Actin-binding Alternative splicing Calmodulin-binding Cytoskeleton Developmental protein Differentiation Intellectual disability Membrane Neurogenesis Phosphoprotein Proteomics identification Reference proteome Sarcoplasmic reticulum Serine/threonine-protein kinase Synapse
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| protein phosphorylation | ||
| signal transduction | ||
| nervous system development |
|
|
| positive regulation of neuron projection development | ||
| regulation of skeletal muscle adaptation |
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
positive regulation of biological process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| actin binding |
|
|
| calcium/calmodulin-dependent protein kinase activity | ||
| calcium/calmodulin-dependent protein kinase activity | ||
| calcium/calmodulin-dependent protein kinase activity | ||
| calmodulin binding |
Sequence
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKAPRVPDILSSVRRGSGAPEAEGPLPCPSPAPFSPLPAPSPRISDILNSVRRGSGTPEAEGPLSAGPPPCLSPALLGPLSSPSPRISDILNSVRRGSGTPEAEGPSPVGPPPCPSPTIPGPLPTPSRKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 177 |
|
|
||
| 320 |
|
|||
| 321 |
|
|||
| 325 |
|
|||
| 328 |
|
|||
| 333 |
|
|||
| 531 |
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Assembly and cell surface presentation of NMDA receptors | Homo sapiens |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | Homo sapiens |
| CaMK IV-mediated phosphorylation of CREB | Homo sapiens |
| Dengue Virus-Host Interactions | Homo sapiens |
| HSF1-dependent transactivation | Homo sapiens |
| Interferon gamma signaling | Homo sapiens |
| Ion homeostasis | Homo sapiens |
| Ion transport by P-type ATPases | Homo sapiens |
| Long-term potentiation | Homo sapiens |
| Negative regulation of NMDA receptor-mediated neuronal transmission | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080230 | autosomal dominant intellectual developmental disorder 54 |
