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MIRAGE
Tumor necrosis factor receptor type 1-associated DEATH domain protein
Summary
- UniProt ID
- Q3U0V2
- Gene Symbol
- Tradd
- Gene ID
- 71609
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
- Apoptosis Cytoskeleton Glycoprotein Nucleus Reference proteome
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| canonical NF-kappaB signal transduction | ||
| canonical NF-kappaB signal transduction | ||
| extrinsic apoptotic signaling pathway via death domain receptors | ||
| extrinsic apoptotic signaling pathway via death domain receptors | ||
| positive regulation of cell migration |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| tumor necrosis factor receptor superfamily complex | ||
| tumor necrosis factor receptor superfamily complex | ||
| tumor necrosis factor receptor superfamily complex | ||
| nucleus | ||
| nucleus |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| transmembrane receptor protein tyrosine kinase adaptor activity | ||
| transmembrane receptor protein tyrosine kinase adaptor activity | ||
| transmembrane receptor protein tyrosine kinase adaptor activity | ||
| tumor necrosis factor receptor binding | ||
| kinase binding |
GO Hierarchy
Sequence
MAAGQNGHEEWVGSAYLFLESAVDKVILSEAYTDPKKKVAIYKALQTALSESGDSSDVLQILKIHCSDPQLIVQLRFCGRVLCGRFLQAYREGALRTALQRCMAPALAQEALRLQLELRAGAEQLDSWLTDEERCLNYILAQKPDRLRDEELAELEDELCKLTCDCTGQGGAIQVASAGSKFPVSSPTEEKPLPAACQTFLFHGQLVVNRPLTLQDQQTFARSVGLKWRRVGRSLQRNCRALRDPALDSLAYEYERDGLYEQAFQLLRRFMQAEGRRATLQRLVEALEENELTSLAEDLLGQAEPDGGLA
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CASP8 activity is inhibited | Mus musculus |
| Dimerization of procaspase-8 | Mus musculus |
| Regulation by c-FLIP | Mus musculus |
| Regulation of TNFR1 signaling | Mus musculus |
| Regulation of necroptotic cell death | Mus musculus |
| TNF signaling | Mus musculus |
| TNFR1-induced NF-kappa-B signaling pathway | Mus musculus |
| TNFR1-induced proapoptotic signaling | Mus musculus |
