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MIRAGE
Leucine-rich repeat serine/threonine-protein kinase 2
Summary
- UniProt ID
- Q5S007
- Gene Symbol
-
- LRRK2
- PARK8
- Gene ID
- 120892
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Autophagy
- Cell projection
- Coiled coil
- Cytoplasmic vesicle
- Cytoskeleton
- Differentiation
- Disease variant
- Endoplasmic reticulum
- Endosome
- GTP-binding
- GTPase activation
- Golgi apparatus
- Hydrolase
- Leucine-rich repeat
- Lysosome
- Mitochondrion outer membrane
- Neurodegeneration
- Parkinson disease
- Parkinsonism
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Repeat
- Serine/threonine-protein kinase
- Synapse
- Ubl conjugation
- WD repeat
- Gene Ontology (GO)
| GO Term |
|---|
| growth cone |
| synaptic vesicle membrane |
| cytoplasmic side of mitochondrial outer membrane |
| terminal bouton |
| perikaryon |
| phagocytic vesicle |
| extracellular exosome |
| extracellular space |
| cytoplasm |
| mitochondrion |
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| PTK6 promotes HIF1A stabilization | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060371 | Parkinson's disease 8 | |
| DOID:0080855 | Parkinsonism | |
| DOID:14330 | Parkinson's disease | |
| DOID:162 | cancer | |
| DOID:8778 | Crohn's disease |
