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Shugoshin 2A

Summary

UniProt ID: Q7TSY8
Gene Symbol: Sgo2 Sgo2a Sgol2 Sgol2a
Gene ID: 68549
Organism: Mus musculus (house mouse)

External Links

PubChem: Q7TSY8
The O-GlcNAc Database: Q7TSY8
Re-Glyco: Q7TSY8

Annotation

Keyword: Cell division Centromere Chromosome Chromosome partition Coiled coil Direct protein sequencing Kinetochore Meiosis Nucleus Phosphoprotein Reference proteome

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	Reference
chromosome segregation
male meiotic nuclear division	IMP	PMID
female meiotic nuclear division	IMP	PMID
protein localization	IMP	PMID
intracellular protein localization	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

cell cycle process [inference]

chromosome segregation

sister chromatid cohesion [inference]

meiotic sister chromatid cohesion

centromeric sister chromatid cohesion [inference]

meiotic sister chromatid cohesion, centromeric

meiotic cell cycle process [inference]

meiotic nuclear division [inference]

cell division

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

organelle fission [inference]

nuclear division [inference]

meiotic nuclear division [inference]

chromosome organization [inference]

sister chromatid cohesion [inference]

meiotic sister chromatid cohesion

centromeric sister chromatid cohesion [inference]

meiotic sister chromatid cohesion, centromeric

reproductive process [inference]

meiotic cell cycle process [inference]

meiotic nuclear division [inference]

localization [inference]

macromolecule localization [inference]

intracellular protein localization

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

regulation of chromosome organization [inference]

regulation of sister chromatid cohesion [inference]

regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

regulation of maintenance of meiotic sister chromatid cohesion, centromeric [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

regulation of centromeric sister chromatid cohesion [inference]

regulation of maintenance of meiotic sister chromatid cohesion, centromeric [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

positive regulation of chromosome organization [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

regulation of sister chromatid cohesion [inference]

regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

regulation of maintenance of meiotic sister chromatid cohesion, centromeric [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

regulation of centromeric sister chromatid cohesion [inference]

regulation of maintenance of meiotic sister chromatid cohesion, centromeric [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

positive regulation of cell cycle process [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	Reference
chromosome, centromeric region	ISO	GO_REF
chromosome, centromeric region	IDA	PMID PMID
chromosome, centromeric region	IEA	GO_REF GO_REF GO_REF
kinetochore	IDA	PMID
kinetochore	IBA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

cohesin complex [inference]

mitotic cohesin complex

cellular anatomical structure [inference]

nucleoplasm

organelle [inference]

membraneless organelle [inference]

intracellular membraneless organelle [inference]

intracellular organelle [inference]

intracellular membraneless organelle [inference]

chromosomal region [inference]

chromosome, centromeric region

condensed chromosome, centromeric region

supramolecular complex [inference]

kinetochore

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MEYPGIKVDTVTSGIQRRVKGRIAKTNLNVSLASKIKAKILNNSSIFKISLKHNNRALARALSKEKENSRRITTEKMQLQKEVEKLNFENTFLRLKLNTLNKKLVEIESHVSNDLLTAIEISSLSEFHQGSFLLSATKKQRNSKQCKPAHLPYARVLLTSENDDDDGADDKWQTKCNNRTISKTSPDSTSSVSRQPSSLHQCNLKAFPPKEDNQKTCGSGHLEHTSSVDILPNESHSDQSPKSSLSEMKTAPSPSLRREKLSHGNVTMRKKCVSSTPDILYVTDLDHQPTSSPGSNWNNEIHGHTNETSNNTQRNAECFLDLPSESSSEPDAKRMELVQKNTDSFHFQKTVYDAADMELTATDIGKIVAVSKSKKNQNKKKADCRKETFRKVKGASSDKKRESSKRECKDGSEVGAEEEADAARAERGAGVLDGRGDSEEPNCISSTEQPSQVNTQKKRTLQNSSDQENIQNTKRRQTYTTDEQEETNPFSRHSVKFLQDGKFDLCQKTLHHNLSKPSRQTFVIRKSEKDNLFPNQEDKDTISENLEVTNEFHIDDLSIEANENVCDHETQTMLDLKKSVSAQQNQTKINKTKQKINRRTKIISVMSQVYEDNDKDIHVLEKDNFPFHTQANKETTSGNLESSKEFESPLLFTRDNGSLRDCKTQNVLDLHKQIPDLYPDRNESQISKIPRQKVNRKTEVISGVKCFSNDQGVHCSEKDKSLLLQKDKDFPGTLKDLSEFDTPAFCNKDSAKSCDYKSEMLLGLKKHDPNMQPACQDDSKAGKKLRQKVNRKTEIISKITQIHENDRGSTHDSLNKKLCQKVNISKIISQMNQIYETINEDGNGFKSSIKDCEDIKSCDFGEINSNKKENYDPIQDPCTLVKKTKRKGSCKAGSSLAGAKNRCGLQLTDSSQVQSVPLDSGLRHHPNEADSGPGEQTNLPKMQKQSAGRSLGDAFSVSLGKEGSRPAKAVSKMTPKSKKRKLPLGCSPETHGTVEITPNTDLAKAVDSQQTEKENYLEKEKIAKRKPDFCTKVLKPLSETCSSNIKNSSLDSMCKSSLPLSISSRKTLMLEESSSLESTCIFQVGDAAHEKITTGTRNPHHRTQKSTPGSRTSLVLVDTSSVSDTNPANPENESEGQSSHPMRRKRQCVPLNLTEPSLRSKMRR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
894		34418053	G49108TO	The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal	Mus musculus
EML4 and NUDC in mitotic spindle formation	Mus musculus
Mitotic Prometaphase	Mus musculus
RHO GTPases Activate Formins	Mus musculus
Resolution of Sister Chromatid Cohesion	Mus musculus
Separation of Sister Chromatids	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

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Acknowledgements