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E3 ubiquitin-protein ligase ZNF598

Summary

UniProt ID: Q80YR4
Gene Symbol: Znf598 Zfp598
Gene ID: 213753
Organism: Mus musculus (house mouse)

External Links

GlyGen: Q80YR4
The O-GlcNAc Database: Q80YR4
O-GlcNAcAtlas: Q80YR4
Re-Glyco: Q80YR4

Annotation

Keyword: Alternative splicing Cytoplasm Phosphoprotein Reference proteome Transferase Translation regulation Ubl conjugation pathway Zinc-finger

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	Reference
protein monoubiquitination	ISS	GO_REF
protein monoubiquitination	ISO	GO_REF
protein ubiquitination	ISS	GO_REF
protein ubiquitination	ISO	GO_REF
protein ubiquitination	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translational elongation [inference]

cytoplasmic translational elongation [inference]

rescue of stalled cytosolic ribosome

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

macromolecule biosynthetic process [inference]

translational elongation [inference]

cytoplasmic translational elongation [inference]

rescue of stalled cytosolic ribosome

protein metabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination [inference]

protein K63-linked ubiquitination

protein monoubiquitination

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination [inference]

protein K63-linked ubiquitination

protein monoubiquitination

primary metabolic process [inference]

protein metabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination [inference]

protein K63-linked ubiquitination

protein monoubiquitination

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

organelle disassembly [inference]

ribosome disassembly

rescue of stalled cytosolic ribosome

cellular component disassembly [inference]

organelle disassembly [inference]

ribosome disassembly

rescue of stalled cytosolic ribosome

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of translational initiation

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of translational initiation

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

regulation of translational initiation [inference]

negative regulation of translational initiation

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of translational initiation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

regulation of translational initiation [inference]

negative regulation of translational initiation

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of translational initiation

regulation of protein metabolic process [inference]

regulation of translation [inference]

regulation of translational initiation [inference]

negative regulation of translational initiation

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of translational initiation

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of translation [inference]

regulation of translational initiation [inference]

negative regulation of translational initiation

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of translational initiation

Displaying **all 4** entries
GO Term	Evidence Code	Reference
cytosol	ISS	GO_REF
cytosol	ISO	GO_REF
cytosol	IEA	GO_REF
cytosolic ribosome	ISO	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytosol

organelle [inference]

membraneless organelle [inference]

intracellular membraneless organelle [inference]

ribosome [inference]

cytosolic ribosome

intracellular organelle [inference]

intracellular membraneless organelle [inference]

ribosome [inference]

cytosolic ribosome

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	Reference
zinc ion binding
ribosome binding	ISS	GO_REF
ribosome binding	ISO	GO_REF
ribosome binding	IBA	GO_REF
ubiquitin-protein transferase regulator activity

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

aminoacyltransferase activity [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity [inference]

ubiquitin protein ligase activity

ubiquitin-like protein ligase activity [inference]

ubiquitin protein ligase activity

catalytic activity, acting on a protein [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity [inference]

ubiquitin protein ligase activity

ubiquitin-like protein ligase activity [inference]

ubiquitin protein ligase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

protein-containing complex binding [inference]

ribonucleoprotein complex binding [inference]

ribosome binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

protein-RNA adaptor activity

molecular function regulator activity [inference]

enzyme regulator activity [inference]

ubiquitin-protein transferase regulator activity

molecular sensor activity [inference]

stalled ribosome sensor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MAAAAGAEGRRAALEAVAAPERGGGSCVLCCGDLEATALGRCDHPVCYRCSTKMRVLCEQRYCAVCREELRQVVFGKKLPAFALIPIHQLQHEKKYDIYFADGKVFALYRQLLQHECPRCPHLPPFSLFGDLEQHMRKQHELFCCKLCLKHLKIFTYERKWYSRKDLARHRMQGDPDDTSHRGHPLCKFCDERYLDNDELLKHLRRDHYFCHFCDSDGAQDYYSDYAYLREHFREKHFLCEEGRCSTEQFTHAFRTEIDLKAHKTACHSRSRAEARQNRQIDLQFSFAPRHSRRSEGVVSGEDYEEVDRYNRQGRAGRASGRGAQQNRRGSWRYKREEEDREVAAAIRASVAAQQQEETQRVEDREEGSRPKKEEAAARVPEEPRGHRRLPRAQGEGSGSKEASANGPVSQEAFPATGPGPVVALSNTLPPPSPELKEEDFPSLCASTSSCCTAVTPGSVGLALAYPGPPRGKNTFQEEDFPALVSSAPKPSSAPSSLISAWNSGCSKKGNLPTPGSQAVVGGSQPPRKAGKGSRGGRKGGPAPVDEEDSGGLTVQGLRSVPTTVAVSSLLAPATNQSSAKVGKKKKVGSEKPGATSSPLLPPDHTPKPSGAEQVLEAPLSKAEVPVTIVVNGHSEGSALVRSAPKEPPGLPRPLGPLPCPIPQEDFPALGGPCPPRMPPPPGFSTVVLLKGTPPPPPPPPGLVPPISKPPPGFSSLLPSSHSACAPSPTTTTTTTTTTKTPGLAPTPQAYLVPENFRERNLQLIQSIKDFLQSDEACFSKFKSHSGEFRQGMISAAQYYKSCRDLLGESFQKIFSELLALLPDTAKQQELLSAHTDFCSREKPPNSRSKRNKKNVWQTSTQQLGLDCCVCPTCQQVLAHGDVSSHQALHAARDDDFPSLQAIARIIT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 9** entries
Position	PubMed ID	GlyTouCan ID	Source
456			GlyGen
514			GlyGen
560	22517741 22645316 25153642 28528544 30059200 35822049 36852467 40021952 40885482 40997131	G49108TO	GlyGen The O-GlcNAc Database
563	22517741 22645316 25153642 28528544 30059200 35822049 36852467 40021952 40885482 40997131	G49108TO	The O-GlcNAc Database
564	22517741 22645316 25153642 28528544 30059200 35822049 36852467 40021952 40885482 40997131	G49108TO	GlyGen The O-GlcNAc Database
569	22517741 22645316 25153642 28528544 30059200 35822049 36852467 40021952 40885482 40997131	G49108TO	The O-GlcNAc Database
621	22517741 22645316 25153642 28528544 30059200 35822049 36852467 40021952 40885482 40997131	G49108TO	The O-GlcNAc Database
628	22517741 22645316 25153642 28528544 30059200 35822049 36852467 40021952 40885482 40997131	G49108TO	The O-GlcNAc Database
747			GlyGen