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MIRAGE
Stimulator of interferon genes protein
Summary
- UniProt ID
- Q86WV6
- Gene Symbol
-
- ERIS
- MITA
- STING
- STING1
- TMEM173
- Gene ID
- 340061
- Organism
- Homo sapiens (human)
External Links
- PubChem
- Q86WV6
- The Human Metabolome Database
- HMDBP12695
- The O-GlcNAc Database
- Q86WV6
- RaftProt
- Q86WV6
- Re-Glyco
- Q86WV6
Annotation
- Keyword
-
- 3D-structure
- Autophagy
- Cell membrane
- Cytoplasm
- Cytoplasmic vesicle
- Disease variant
- Endoplasmic reticulum
- Golgi apparatus
- Host-virus interaction
- Innate immunity
- Ion channel
- Isopeptide bond
- Mitochondrion outer membrane
- Nucleotide-binding
- Palmitate
- Phosphoprotein
- Reference proteome
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| autophagosome membrane |
| mitochondrial outer membrane |
| autophagosome |
| peroxisome |
| endoplasmic reticulum-Golgi intermediate compartment membrane |
| serine/threonine protein kinase complex |
| GO Term |
|---|
| positive regulation of defense response to virus by host |
| autophagosome assembly |
| activation of innate immune response |
Sequence
MPHSSLHPSIPCPRGHGAQKAALVLLSACLVTLWGLGEPPEHTLRYLVLHLASLQLGLLLNGVCSLAEELRHIHSRYRGSYWRTVRACLGCPLRRGALLLLSIYFYYSLPNAVGPPFTWMLALLGLSQALNILLGLKGLAPAEISAVCEKGNFNVAHGLAWSYYIGYLRLILPELQARIRTYNQHYNNLLRGAVSQRLYILLPLDCGVPDNLSMADPNIRFLDKLPQQTGDHAGIKDRVYSNSIYELLENGQRAGTCVLEYATPLQTLFAMSQYSQAGFSREDRLEQAKLFCRTLEDILADAPESQNNCRLIAYQEPADDSSFSLSQEVLRHLRQEEKEEVTVGSLKTSAVPSTSTMSQEPELLISGMEKPLPLRTDFS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 229 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| IRF3-mediated induction of type I IFN | Homo sapiens |
| Neutrophil degranulation | Homo sapiens |
| Regulation of innate immune responses to cytosolic DNA | Homo sapiens |
| SARS-CoV-1 activates/modulates innate immune responses | Homo sapiens |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | Homo sapiens |
| STAT6-mediated induction of chemokines | Homo sapiens |
| STING mediated induction of host immune responses | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0111457 | STING-associated vasculopathy with onset in infancy |
