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Ectonucleoside triphosphate diphosphohydrolase 8

Summary

UniProt ID: Q8K0L2
Gene Symbol: Entpd8
Gene ID: 72090
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0006734
PubChem: Q8K0L2
Re-Glyco: Q8K0L2

Annotation

Keyword: ATP-binding Alternative splicing Calcium Cell membrane Disulfide bond Glycoprotein Hydrolase Magnesium Metal-binding Reference proteome Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	Reference
nucleoside monophosphate biosynthetic process	IDA	PMID
nucleoside diphosphate biosynthetic process	IDA	PMID
nucleoside diphosphate catabolic process	IBA	GO_REF
ribonucleoside diphosphate catabolic process	ISO	GO_REF GO_REF
ribonucleoside diphosphate catabolic process	IDA	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside monophosphate metabolic process [inference]

nucleoside monophosphate biosynthetic process

nucleoside diphosphate metabolic process [inference]

nucleoside diphosphate biosynthetic process

nucleoside diphosphate catabolic process

ribonucleoside diphosphate catabolic process

ribonucleoside diphosphate metabolic process [inference]

ribonucleoside diphosphate catabolic process

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process [inference]

ribonucleoside triphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

ribonucleoside diphosphate catabolic process

nucleoside triphosphate catabolic process [inference]

ribonucleoside triphosphate catabolic process

nucleoside phosphate biosynthetic process [inference]

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside monophosphate metabolic process [inference]

nucleoside monophosphate biosynthetic process

nucleoside diphosphate metabolic process [inference]

nucleoside diphosphate biosynthetic process

nucleoside diphosphate catabolic process

ribonucleoside diphosphate catabolic process

ribonucleoside diphosphate metabolic process [inference]

ribonucleoside diphosphate catabolic process

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process [inference]

ribonucleoside triphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

ribonucleoside diphosphate catabolic process

nucleoside triphosphate catabolic process [inference]

ribonucleoside triphosphate catabolic process

nucleoside phosphate biosynthetic process [inference]

organophosphate catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

ribonucleoside diphosphate catabolic process

nucleoside triphosphate catabolic process [inference]

ribonucleoside triphosphate catabolic process

organophosphate biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

ribonucleoside diphosphate catabolic process

nucleoside triphosphate catabolic process [inference]

ribonucleoside triphosphate catabolic process

organophosphate catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

ribonucleoside diphosphate catabolic process

nucleoside triphosphate catabolic process [inference]

ribonucleoside triphosphate catabolic process

biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

organophosphate biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

ribonucleoside diphosphate catabolic process

nucleoside triphosphate catabolic process [inference]

ribonucleoside triphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside monophosphate metabolic process [inference]

nucleoside monophosphate biosynthetic process

nucleoside diphosphate metabolic process [inference]

nucleoside diphosphate biosynthetic process

nucleoside diphosphate catabolic process

ribonucleoside diphosphate catabolic process

ribonucleoside diphosphate metabolic process [inference]

ribonucleoside diphosphate catabolic process

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process [inference]

ribonucleoside triphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

ribonucleoside diphosphate catabolic process

nucleoside triphosphate catabolic process [inference]

ribonucleoside triphosphate catabolic process

nucleoside phosphate biosynthetic process [inference]

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside monophosphate metabolic process [inference]

nucleoside monophosphate biosynthetic process

nucleoside diphosphate metabolic process [inference]

nucleoside diphosphate biosynthetic process

nucleoside diphosphate catabolic process

ribonucleoside diphosphate catabolic process

ribonucleoside diphosphate metabolic process [inference]

ribonucleoside diphosphate catabolic process

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process [inference]

ribonucleoside triphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

ribonucleoside diphosphate catabolic process

nucleoside triphosphate catabolic process [inference]

ribonucleoside triphosphate catabolic process

nucleoside phosphate biosynthetic process [inference]

Displaying **all 5** entries
GO Term	Evidence Code	Reference
plasma membrane	ISS	GO_REF
plasma membrane	ISO	GO_REF
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF
membrane	IDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	Reference
apyrase activity	ISO	GO_REF GO_REF
apyrase activity	IDA	PMID
apyrase activity	IEA	GO_REF GO_REF GO_REF
GDP phosphatase activity	IBA	GO_REF
ATP binding

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

apyrase activity

nucleoside diphosphate phosphatase activity

ribonucleoside triphosphate phosphatase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MGLSWKERVFMALLGVAAASGLTMLVLILVKAINVLLPADTKFGIVFDAGSSHTSLFVYQWPANKEKDTGVVSQALTCQIEGPGISSYTSDPTQAGESLKSCLEEALALIPQAQHPETPTFLGSTAGMRLLSQKNSSQARDILAAVSQTLSKSPVDFWGAKILAGQDEGAFGWITINYVLGMLLKYSSGQWILPEEGMLVGALDLGGASTQISFVPQGPILDQSTQVTFRLYGANYSVYTHSYLCFGRDQILNRLLAKLAQDRLSSQVAPVRHPCYHSGYQAILPLSSLYDSPCIHTTDSLNHTQNLTVEGTGDPGNCVVALRSLFNFSSCKGQKDCAFNGIYQPPVHGQFYAFSNFYYTFHFLNLTSRQSLNTVNDTVWKFCQKPWKLVEVSYPGQERWLRDYCASGLYILVLLLEGYKFSEETWPNIQFQKQAGDTDIGWTLGFMLNLTGMIPAEAPTHWRAQSYSIWTAGVVFAVLTLVAILGAAAIQIFWTQD

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites