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Organic anion transporter 3

Summary

UniProt ID: Q8TCC7
Gene Symbol: SLC22A8 OAT3
Gene ID: 9376
Organism: Homo sapiens (human)

External Links

GlyGen: Q8TCC7
PubChem: Q8TCC7
Re-Glyco: Q8TCC7

Annotation

Keyword: Alternative splicing Cell membrane Detoxification Glycoprotein Ion transport Lipid transport Phosphoprotein Proteomics identification Reference proteome Transmembrane helix

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	Reference
response to toxic substance
organic anion transport
prostaglandin transport	IDA	PMID
transport across blood-brain barrier	NAS	PMID

GO Hierarchy

biological process

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

vascular transport [inference]

transport across blood-brain barrier

response to stimulus [inference]

response to chemical [inference]

response to toxic substance

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport

lipid transport [inference]

fatty acid transport [inference]

prostaglandin transport

vascular transport [inference]

transport across blood-brain barrier

organic anion transport

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

fatty acid transport [inference]

prostaglandin transport

icosanoid transport [inference]

prostaglandin transport

organic acid transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

fatty acid transport [inference]

prostaglandin transport

icosanoid transport [inference]

prostaglandin transport

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
plasma membrane	TAS	Reactome
basolateral plasma membrane	ISS	PMID
basolateral plasma membrane	IDA	PMID PMID PMID
basolateral plasma membrane	IEA	GO_REF
apical plasma membrane	ISS	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 4** entries
GO Term	Evidence Code	Reference
solute:inorganic anion antiporter activity	IDA	PMID
obsolete organic anion transmembrane transporter activity
prostaglandin transmembrane transporter activity	IDA	PMID
xenobiotic transmembrane transporter activity	IDA	PMID

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

antiporter activity [inference]

solute:inorganic anion antiporter activity

xenobiotic transmembrane transporter activity

lipid transmembrane transporter activity [inference]

icosanoid transmembrane transporter activity [inference]

prostaglandin transmembrane transporter activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MTFSEILDRVGSMGHFQFLHVAILGLPILNMANHNLLQIFTAATPVHHCRPPHNASTGPWVLPMGPNGKPERCLRFVHPPNASLPNDTQRAMEPCLDGWVYNSTKDSIVTEWDLVCNSNKLKEMAQSIFMAGILIGGLVLGDLSDRFGRRPILTCSYLLLAASGSGAAFSPTFPIYMVFRFLCGFGISGITLSTVILNVEWVPTRMRAIMSTALGYCYTFGQFILPGLAYAIPQWRWLQLTVSIPFFVFFLSSWWTPESIRWLVLSGKSSKALKILRRVAVFNGKKEEGERLSLEELKLNLQKEISLAKAKYTASDLFRIPMLRRMTFCLSLAWFATGFAYYSLAMGVEEFGVNLYILQIIFGGVDVPAKFITILSLSYLGRHTTQAAALLLAGGAILALTFVPLDLQTVRTVLAVFGKGCLSSSFSCLFLYTSELYPTVIRQTGMGVSNLWTRVGSMVSPLVKITGEVQPFIPNIIYGITALLGGSAALFLPETLNQPLPETIEDLENWSLRAKKPKQEPEVEKASQRIPLQPHGPGLGSS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
86	N-linked (GlcNAc...) asparagine			UniProt GlyGen
102	N-linked (GlcNAc...) asparagine	37074911	G01160VV G60967DT G57776ZS G44753VC G68490OW G80479JV G85282JO G87123QX G79666IR G07246CJ G40926MX G49906RN G27915IV G70441OD G29184RN G96091TT G60033FS G41071NU G49018RC G80920RR G65184UU G02886BB G59924QI G88891KO G28541PG G02815KT	UniProt GlyGen