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Scavenger receptor class B member 1

Summary

UniProt ID: Q8WTV0
Gene Symbol: SCARB1 CD36L1 CLA1
Gene ID: 949
Organism: Homo sapiens (human)

External Links

GlyConnect

Scavenger receptor class B member 1

GlyGen

Q8WTV0

PubChem

Q8WTV0

SwissLipids

SLP:000001519

The Human Metabolome Database

HMDBP02237

RaftProt

Q8WTV0

Re-Glyco

Q8WTV0

Annotation

Keyword: Alternative splicing Cell membrane Disulfide bond Glycoprotein Host cell receptor for virus entry Host-virus interaction Palmitate Phosphoprotein Proteomics identification Reference proteome Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 44 in total

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GO Term	Evidence Code	Reference
endothelial cell proliferation
cholesterol catabolic process
positive regulation of endothelial cell migration	TAS	PMID
positive regulation of nitric oxide mediated signal transduction
positive regulation of triglyceride biosynthetic process	ISS	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

lipoprotein particle mediated signaling [inference]

high density lipoprotein particle mediated signaling

cell recognition [inference]

phagocytosis, recognition [inference]

recognition of apoptotic cell

metabolic process [inference]

catabolic process [inference]

lipid catabolic process [inference]

steroid catabolic process [inference]

sterol catabolic process [inference]

cholesterol catabolic process

small molecule catabolic process [inference]

alcohol catabolic process [inference]

cholesterol catabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid catabolic process [inference]

sterol catabolic process [inference]

cholesterol catabolic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol catabolic process

sterol catabolic process [inference]

cholesterol catabolic process

lipid catabolic process [inference]

steroid catabolic process [inference]

sterol catabolic process [inference]

cholesterol catabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

alcohol catabolic process [inference]

cholesterol catabolic process

secondary alcohol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol catabolic process

small molecule catabolic process [inference]

alcohol catabolic process [inference]

cholesterol catabolic process

cell population proliferation [inference]

epithelial cell proliferation [inference]

endothelial cell proliferation

cell motility [inference]

cell migration [inference]

endothelial cell migration [inference]

blood vessel endothelial cell migration

transmembrane transport [inference]

vitamin transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-containing complex remodeling [inference]

protein-lipid complex remodeling [inference]

plasma lipoprotein particle remodeling [inference]

high-density lipoprotein particle remodeling

protein-lipid complex organization [inference]

protein-lipid complex remodeling [inference]

plasma lipoprotein particle remodeling [inference]

high-density lipoprotein particle remodeling

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle remodeling [inference]

high-density lipoprotein particle remodeling

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

vasodilation

digestive system process [inference]

intestinal absorption [inference]

intestinal lipid absorption

plasma lipoprotein particle clearance

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle remodeling [inference]

high-density lipoprotein particle remodeling

homeostatic process [inference]

chemical homeostasis [inference]

lipid homeostasis [inference]

acylglycerol homeostasis [inference]

triglyceride homeostasis

sterol homeostasis [inference]

cholesterol homeostasis

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

adhesion of symbiont to host

response to stimulus [inference]

response to stress [inference]

response to wounding [inference]

wound healing

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

detection of molecule of bacterial origin [inference]

detection of lipopolysaccharide

response to lipopolysaccharide [inference]

detection of lipopolysaccharide

detection of external biotic stimulus [inference]

detection of molecule of bacterial origin [inference]

detection of lipopolysaccharide

response to biotic stimulus [inference]

detection of biotic stimulus [inference]

detection of external biotic stimulus [inference]

detection of molecule of bacterial origin [inference]

detection of lipopolysaccharide

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

detection of molecule of bacterial origin [inference]

detection of lipopolysaccharide

response to lipopolysaccharide [inference]

detection of lipopolysaccharide

detection of external biotic stimulus [inference]

detection of molecule of bacterial origin [inference]

detection of lipopolysaccharide

response to chemical [inference]

response to lipid [inference]

response to lipopolysaccharide [inference]

detection of lipopolysaccharide

response to oxygen-containing compound [inference]

response to lipopolysaccharide [inference]

detection of lipopolysaccharide

detection of stimulus [inference]

detection of chemical stimulus [inference]

detection of molecule of bacterial origin [inference]

detection of lipopolysaccharide

detection of biotic stimulus [inference]

detection of external biotic stimulus [inference]

detection of molecule of bacterial origin [inference]

detection of lipopolysaccharide

localization [inference]

establishment of localization [inference]

transport [inference]

lipid transport [inference]

phospholipid transport

sterol transport [inference]

cholesterol transport [inference]

lipopolysaccharide transport

organophosphate ester transport [inference]

phospholipid transport

organic hydroxy compound transport [inference]

sterol transport [inference]

cholesterol transport [inference]

vitamin transport [inference]

vitamin transmembrane transport

transmembrane transport [inference]

vitamin transmembrane transport

carbohydrate derivative transport [inference]

lipopolysaccharide transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of sphingolipid mediated signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of nitric oxide mediated signal transduction

regulation of sphingolipid mediated signaling pathway [inference]

positive regulation of sphingolipid mediated signaling pathway

regulation of intracellular signal transduction [inference]

regulation of nitric oxide mediated signal transduction [inference]

positive regulation of nitric oxide mediated signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of nitric oxide mediated signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of sphingolipid mediated signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of nitric oxide mediated signal transduction

regulation of localization [inference]

regulation of transport [inference]

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

regulation of phagocytosis

regulation of lipid localization [inference]

positive regulation of lipid localization [inference]

positive regulation of lipid storage [inference]

positive regulation of cholesterol storage

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of sphingolipid mediated signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of nitric oxide mediated signal transduction

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of triglyceride biosynthetic process

positive regulation of lipid metabolic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of triglyceride biosynthetic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride biosynthetic process

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of sphingolipid mediated signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of nitric oxide mediated signal transduction

positive regulation of lipid storage [inference]

positive regulation of cholesterol storage

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of sphingolipid mediated signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of nitric oxide mediated signal transduction

positive regulation of lipid localization [inference]

positive regulation of lipid storage [inference]

positive regulation of cholesterol storage

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of sphingolipid mediated signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of nitric oxide mediated signal transduction

regulation of sphingolipid mediated signaling pathway [inference]

positive regulation of sphingolipid mediated signaling pathway

regulation of intracellular signal transduction [inference]

regulation of nitric oxide mediated signal transduction [inference]

positive regulation of nitric oxide mediated signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of nitric oxide mediated signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of sphingolipid mediated signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of nitric oxide mediated signal transduction

regulation of cellular process [inference]

signal transduction [inference]

lipoprotein particle mediated signaling [inference]

high density lipoprotein particle mediated signaling

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of sphingolipid mediated signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of nitric oxide mediated signal transduction

regulation of sphingolipid mediated signaling pathway [inference]

positive regulation of sphingolipid mediated signaling pathway

regulation of intracellular signal transduction [inference]

regulation of nitric oxide mediated signal transduction [inference]

positive regulation of nitric oxide mediated signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of nitric oxide mediated signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of sphingolipid mediated signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of nitric oxide mediated signal transduction

regulation of lipid storage [inference]

positive regulation of lipid storage [inference]

positive regulation of cholesterol storage

regulation of cholesterol storage [inference]

positive regulation of cholesterol storage

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of triglyceride biosynthetic process

regulation of lipid biosynthetic process [inference]

regulation of triglyceride biosynthetic process [inference]

positive regulation of triglyceride biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of triglyceride biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of triglyceride biosynthetic process

positive regulation of lipid metabolic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of triglyceride biosynthetic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride biosynthetic process

regulation of catabolic process [inference]

regulation of lipid catabolic process [inference]

regulation of phospholipid catabolic process [inference]

regulation of phosphatidylcholine catabolic process

regulation of phosphorus metabolic process [inference]

regulation of phospholipid metabolic process [inference]

regulation of phospholipid catabolic process [inference]

regulation of phosphatidylcholine catabolic process

regulation of phosphatidylcholine metabolic process [inference]

regulation of phosphatidylcholine catabolic process

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

positive regulation of lipid metabolic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of triglyceride biosynthetic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride biosynthetic process

regulation of lipid biosynthetic process [inference]

regulation of triglyceride biosynthetic process [inference]

positive regulation of triglyceride biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of triglyceride biosynthetic process

regulation of lipid catabolic process [inference]

regulation of phospholipid catabolic process [inference]

regulation of phosphatidylcholine catabolic process

regulation of triglyceride metabolic process [inference]

regulation of triglyceride biosynthetic process [inference]

positive regulation of triglyceride biosynthetic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride biosynthetic process

regulation of phospholipid metabolic process [inference]

regulation of phospholipid catabolic process [inference]

regulation of phosphatidylcholine catabolic process

regulation of phosphatidylcholine metabolic process [inference]

regulation of phosphatidylcholine catabolic process

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of triglyceride biosynthetic process

positive regulation of lipid metabolic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of triglyceride biosynthetic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride biosynthetic process

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of sphingolipid mediated signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of nitric oxide mediated signal transduction

positive regulation of lipid storage [inference]

positive regulation of cholesterol storage

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

regulation of phagocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

regulation of phagocytosis

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration

regulation of biological quality [inference]

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

vasodilation

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GO Term	Evidence Code	Reference
lysosome
lysosomal membrane	HDA	PMID
plasma membrane	EXP	PMID
plasma membrane	TAS	Reactome Reactome Reactome Reactome
plasma membrane	IDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cell surface

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endocytic vesicle membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

endocytic vesicle membrane

plasma membrane region [inference]

plasma membrane raft [inference]

caveola

membrane microdomain [inference]

membrane raft [inference]

plasma membrane raft [inference]

caveola

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

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GO Term	Evidence Code	Reference
lipopolysaccharide binding	IDA	PMID
amyloid-beta binding	IEA	GO_REF
virus receptor activity
phosphatidylserine binding	ISS	GO_REF
lipopolysaccharide immune receptor activity	IDA	PMID

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

apolipoprotein binding

apolipoprotein A-I binding

exogenous protein binding [inference]

virus receptor activity

lipid binding

lipopolysaccharide binding

phospholipid binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

phosphatidylserine binding

peptide binding [inference]

amyloid-beta binding

protein-containing complex binding [inference]

protein-lipid complex binding [inference]

lipoprotein particle binding [inference]

modified amino acid binding [inference]

phosphatidylserine binding

carbohydrate derivative binding [inference]

lipopolysaccharide binding

cargo receptor activity [inference]

scavenger receptor activity

lipoprotein particle receptor activity [inference]

high-density lipoprotein particle receptor activity

molecular transducer activity [inference]

signaling receptor activity [inference]

pattern recognition receptor activity [inference]

lipopolysaccharide immune receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MGCSAKARWAAGALGVAGLLCAVLGAVMIVMVPSLIKQQVLKNVRIDPSSLSFNMWKEIPIPFYLSVYFFDVMNPSEILKGEKPQVRERGPYVYREFRHKSNITFNNNDTVSFLEYRTFQFQPSKSHGSESDYIVMPNILVLGAAVMMENKPMTLKLIMTLAFTTLGERAFMNRTVGEIMWGYKDPLVNLINKYFPGMFPFKDKFGLFAELNNSDSGLFTVFTGVQNISRIHLVDKWNGLSKVDFWHSDQCNMINGTSGQMWPPFMTPESSLEFYSPEACRSMKLMYKESGVFEGIPTYRFVAPKTLFANGSIYPPNEGFCPCLESGIQNVSTCRFSAPLFLSHPHFLNADPVLAEAVTGLHPNQEAHSLFLDIHPVTGIPMNCSVKLQLSLYMKSVAGIGQTGKIEPVVLPLLWFAESGAMEGETLHTFYTQLVLMPKVMHYAQYVLLALGCVLLLVPVICQIRSQVGAGQRAARADSHSLACWGKGASDRTLWPTAAWSPPPAAVLRLCRSGSGHCWGLRSTLASFACRVATTLPVLEGLGPSLGGGTGS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

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Position	Description	PubMed ID	GlyTouCan ID	Source
54		24190977		GlyGen
102	N-linked (GlcNAc...) asparagine	19159218 24190977	G92942VI	UniProt GlyGen
106		24190977		GlyGen
107		24190977		GlyGen
108	N-linked (GlcNAc...) asparagine	24190977	G71125PP	UniProt GlyGen
173	N-linked (GlcNAc...) asparagine			UniProt GlyGen
212	N-linked (GlcNAc...) asparagine	37074911	G11101UV G05962QB G69521XL G40834TG	UniProt GlyGen
227	N-linked (GlcNAc...) asparagine	29741879	G63332OE G64527OM	UniProt GlyGen GlyConnect
255	N-linked (GlcNAc...) asparagine		G37399XV	UniProt GlyGen
310	N-linked (GlcNAc...) asparagine			UniProt GlyGen