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Lipase member H

Summary

UniProt ID: Q8WWY8
Gene Symbol: LIPH LPDLR MPAPLA1 PLA1B
Gene ID: 200879
Organism: Homo sapiens (human)

External Links

PubChem

Q8WWY8

SwissLipids

SLP:000000625

The Human Metabolome Database

HMDBP07317

Re-Glyco

Q8WWY8

Annotation

Keyword: Cell membrane Disease variant Disulfide bond Glycoprotein Heparin-binding Hydrolase Hypotrichosis Lipid degradation Proteomics identification Reference proteome Secreted Signal

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	Reference
phosphatidic acid biosynthetic process	TAS	Reactome
phosphatidic acid biosynthetic process	IEA	GO_REF
lipid catabolic process	IDA	PMID
lipid catabolic process	IBA	GO_REF
lipid catabolic process	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidic acid metabolic process [inference]

phosphatidic acid biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidic acid biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidic acid biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidic acid metabolic process [inference]

phosphatidic acid biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidic acid biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidic acid biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidic acid biosynthetic process

catabolic process [inference]

lipid catabolic process

biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidic acid biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidic acid biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidic acid biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidic acid metabolic process [inference]

phosphatidic acid biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidic acid biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidic acid biosynthetic process

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidic acid biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidic acid biosynthetic process

lipid catabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidic acid metabolic process [inference]

phosphatidic acid biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidic acid biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidic acid biosynthetic process

Displaying **all 5** entries
GO Term	Evidence Code	Reference
obsolete extracellular space
plasma membrane	EXP	PMID
plasma membrane	TAS	Reactome
plasma membrane	IDA	PMID
plasma membrane	IEA	GO_REF GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
glycerophospholipase activity	TAS	Reactome
glycerophospholipase activity	IDA	PMID
glycerophospholipase activity	IBA	GO_REF
glycerophospholipase activity	IEA	GO_REF
heparin binding	IDA	PMID

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

lipase activity [inference]

phospholipase activity [inference]

glycerophospholipase activity

carboxylic ester hydrolase activity

binding [inference]

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

sulfur compound binding [inference]

heparin binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MLRFYLFISLLCLSRSDAEETCPSFTRLSFHSAVVGTGLNVRLMLYTRKNLTCAQTINSSAFGNLNVTKKTTFIVHGFRPTGSPPVWMDDLVKGLLSVEDMNVVVVDWNRGATTLIYTHASSKTRKVAMVLKEFIDQMLAEGASLDDIYMIGVSLGAHISGFVGEMYDGWLGRITGLDPAGPLFNGKPHQDRLDPSDAQFVDVIHSDTDALGYKEPLGNIDFYPNGGLDQPGCPKTILGGFQYFKCDHQRSVYLYLSSLRESCTITAYPCDSYQDYRNGKCVSCGTSQKESCPLLGYYADNWKDHLRGKDPPMTKAFFDTAEESPFCMYHYFVDIITWNKNVRRGDITIKLRDKAGNTTESKINHEPTTFQKYHQVSLLARFNQDLDKVAAISLMFSTGSLIGPRYKLRILRMKLRSLAHPERPQLCRYDLVLMENVETVFQPILCPELQL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	Source
50	N-linked (GlcNAc...) asparagine	UniProt
66	N-linked (GlcNAc...) asparagine	UniProt
357	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Synthesis of PA	Homo sapiens

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0110704	hypotrichosis 7	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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External Links

Annotation

International Collaboration

Acknowledgements