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MIRAGE

FERM, ARHGEF and pleckstrin domain-containing protein 2

Summary

UniProt ID: Q91VS8
Gene Symbol: Farp2 Kiaa0793
Gene ID: 227377
Organism: Mus musculus (house mouse)

External Links

GlyGen: Q91VS8
PubChem: Q91VS8
O-GlcNAcAtlas: Q91VS8
Re-Glyco: Q91VS8

Annotation

Keyword: 3D-structure Guanine-nucleotide releasing factor Phosphoprotein Reference proteome Repeat

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

1

2

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GO Term	Evidence Code	Reference
cell adhesion	IMP	PMID
neuron remodeling	ISO	PMID
Rac protein signal transduction	ISO	PMID
hair cycle process	IMP	PMID
actin cytoskeleton organization	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

signal transduction [inference]

cell surface receptor signaling pathway [inference]

semaphorin-plexin signaling pathway

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

small GTPase-mediated signal transduction [inference]

Rac protein signal transduction

actin filament-based process [inference]

actin cytoskeleton organization

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

osteoclast differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

osteoclast differentiation

cell maturation [inference]

neuron maturation [inference]

neuron remodeling

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization

organelle assembly [inference]

membraneless organelle assembly [inference]

podosome assembly

cellular component assembly [inference]

protein-containing complex assembly [inference]

podosome assembly

organelle assembly [inference]

membraneless organelle assembly [inference]

podosome assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

podosome assembly

multicellular organismal process [inference]

molting cycle process [inference]

hair cycle process

developmental process [inference]

developmental maturation [inference]

anatomical structure maturation [inference]

cell maturation [inference]

neuron maturation [inference]

neuron remodeling

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

osteoclast differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

osteoclast differentiation

cell maturation [inference]

neuron maturation [inference]

neuron remodeling

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

semaphorin-plexin signaling pathway

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

small GTPase-mediated signal transduction [inference]

Rac protein signal transduction

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly [inference]

regulation of integrin activation

regulation of cellular component organization [inference]

regulation of protein-containing complex assembly [inference]

regulation of integrin activation

Displaying **all 4** entries
GO Term	Evidence Code	Reference
cytoplasm	ISO	PMID
cytoplasm	IEA	GO_REF
cytosol	TAS	Reactome Reactome
cytosol	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

Displaying entries **1 - 5** of 6 in total

1

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GO Term	Evidence Code	Reference
guanyl-nucleotide exchange factor activity	ISO	PMID
guanyl-nucleotide exchange factor activity	TAS	Reactome
guanyl-nucleotide exchange factor activity	IDA	PMID
guanyl-nucleotide exchange factor activity	IBA	GO_REF
guanyl-nucleotide exchange factor activity	IEA	GO_REF GO_REF GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

cytoskeletal protein binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

guanyl-nucleotide exchange factor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MGEIEGTYRALPTSGTRLGGQTAIGVSTLEPEQSLSPRMQEKHMRIRVKLLDSTVELFDIEPKCDGQVLLTQVWKHLNLIECDYFGLEFKNVQSYWIWLEPMKPIIRQVRKPKNAVLRLAVKFFPPDPGQLQEEYTRYLFALQLKRDLLEERLTCTANTAALLISHLLQSEIGDYDETLDREHLKANEYLPNQEKSLEKILDFHQRHTGQTPAESDFQVLEIARKLEMYGIRFHMASDREGTKINLAVSHMGVLVFQGTTKINTFNWSKVRKLSFKRKRFLIKLHPEVHGPYQDTLEFLLGSRDECKNFWKICVEYHTFFRLSDQPKPKAKAVFFSRGSSFRYSGRTQKQLVDYVKDGGMKRIPYERRHSKTRTSLHALTVDLPKQSVSFTDGLRTSASLSSANVSFYPPPSSSLSPPGLPNLKDSSSSLVDPQAPVIKSTAAERSSGPSSSDGPSTQSAHLPGPPVLRPGPGFSMDSPQPSPSSLKSHLSLCPELQAALSTAEQGASPVLSPVLSGAGTARMDNQEEQKHKHMPEDEAYFIAKEILATERTYLKDLEVITVWFRSVLIKEEAMPAALMALLFSNIDPVYEFHRGFLHEVEQRLALWEGPSSAHLKGDHQRIGDILLRNMRQLKEFTSYFQRHDEVLTELEKATKHCKKLEAVYKEFELQKVCYLPLNTFLLKPVQRLVHYRLLLSRLCAHYSPGHRDYADCHEALKAITEVTTELQQSLTRLENLQKLTELQRDLVGVENLIAPGREFIREGCLHKLTKKGLQQRMFFLFSDMLLYTSKSVTGASHFRIRGFLPLRGMLVEESENEWSVPHCFTIYAAQKTIVVAASTRLEKEKWMQDLNAAIQAAKTIGDSPPVLLGGPVYTRTPRSSDEVSLEESEDGRGNRGSLEGNSQHRANTTMHVCWYRNTSVSRADHSAAVENQLSGYLLRKFKNSNGWQKLWVVFTNFCLFFYKTHQDDYPLASLPLLGYSVSLPREADSIHKDYVFKLQFKSHVYFFRAESKYTFERWMDVIKRASSSPGRPPSFTQDCSHHSPGLEAEIREKEACPSPCLDKNL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
71			G49108TO	GlyGen
907			G99679NM	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
RAC1 GTPase cycle	Mus musculus
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	Mus musculus
SRC activates STAT3 in a quantitative manner, through Cadherin-11 (CDH11), RAC1 and gp130 (IL6ST)	Mus musculus

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026