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SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion

Summary

Organism

Mus musculus (house mouse)

Reactome

R-MMU-399955

PubChem

R-MMU-399955

Description

This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 9** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O08665	Semaphorin-3A	SemD Sema3a Semad	view
O70161	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Kiaa0589 Pip5k1c	view
P26039	Talin-1	Tln Tln1	view
P70206	Plexin-A1	Kiaa4053 Plxna1	view
P70207	Plexin-A2	Kiaa0463 Plxna2	view
P70208	Plexin-A3	Plxna3 RP23-436K3.11-001	view
P97333	Neuropilin-1	Nrp Nrp1	view
Q80UG2	Plexin-A4	Kiaa1550 Plxna4	view
Q91VS8	FERM, ARHGEF and pleckstrin domain-containing protein 2	Farp2 Kiaa0793	view

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