GlyCosmos Portal

Submissions

Beta-1,3-galactosyltransferase 6

Summary

UniProt ID: Q96L58
Gene Symbol: B3GALT6
Gene ID: 126792
Organism: Homo sapiens (human)

External Links

GlyConnect

Beta-1,3-galactosyltransferase 6

GlyGen

Q96L58

PubChem

Q96L58

The Human Metabolome Database

HMDBP03281

Re-Glyco

Q96L58

Annotation

Keyword: Disease variant Dwarfism Ehlers-Danlos syndrome Glycoprotein Glycosyltransferase Golgi apparatus Manganese Proteomics identification Reference proteome Signal-anchor Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

1

2

Next ›

Last »
GO Term	Evidence Code	Reference
glycosaminoglycan biosynthetic process	IMP	PMID
glycosaminoglycan biosynthetic process	IBA	GO_REF
glycosaminoglycan biosynthetic process	IEA	GO_REF
protein O-linked glycosylation
heparan sulfate proteoglycan biosynthetic process	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan metabolic process [inference]

heparan sulfate proteoglycan biosynthetic process

chondroitin sulfate proteoglycan metabolic process [inference]

chondroitin sulfate proteoglycan biosynthetic process

dermatan sulfate proteoglycan metabolic process [inference]

dermatan sulfate proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process

primary metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan metabolic process [inference]

heparan sulfate proteoglycan biosynthetic process

chondroitin sulfate proteoglycan metabolic process [inference]

chondroitin sulfate proteoglycan biosynthetic process

dermatan sulfate proteoglycan metabolic process [inference]

dermatan sulfate proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan metabolic process [inference]

heparan sulfate proteoglycan biosynthetic process

chondroitin sulfate proteoglycan metabolic process [inference]

chondroitin sulfate proteoglycan biosynthetic process

dermatan sulfate proteoglycan metabolic process [inference]

dermatan sulfate proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process

Displaying entries **1 - 5** of 8 in total

1

2

Next ›

Last »
GO Term	Evidence Code	Reference
Golgi membrane	TAS	Reactome Reactome
Golgi apparatus	IMP	PMID
Golgi apparatus	IEA	GO_REF
Golgi medial cisterna	IDA	PMID
Golgi medial cisterna	IEA	GO_REF GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

organelle membrane [inference]

Golgi cisterna membrane

bounding membrane of organelle [inference]

Golgi membrane

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

Golgi cisterna [inference]

Golgi medial cisterna

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	Reference
UDP-galactosyltransferase activity	IDA	PMID
galactosylxylosylprotein 3-beta-galactosyltransferase activity	EXP	PMID PMID
galactosylxylosylprotein 3-beta-galactosyltransferase activity	TAS	Reactome Reactome
galactosylxylosylprotein 3-beta-galactosyltransferase activity	IMP	PMID
galactosylxylosylprotein 3-beta-galactosyltransferase activity	IBA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

UDP-galactosyltransferase activity

galactosylxylosylprotein 3-beta-galactosyltransferase activity

hexosyltransferase activity [inference]

galactosyltransferase activity [inference]

UDP-galactosyltransferase activity

galactosylxylosylprotein 3-beta-galactosyltransferase activity

catalytic activity, acting on a protein [inference]

catalytic activity, acting on a glycoprotein [inference]

galactosylxylosylprotein 3-beta-galactosyltransferase activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MKLLRRAWRRRAALGLGTLALCGAALLYLARCAAEPGDPRAMSGRSPPPPAPARAAAFLAVLVASAPRAAERRSVIRSTWLARRGAPGDVWARFAVGTAGLGAEERRALEREQARHGDLLLLPALRDAYENLTAKVLAMLAWLDEHVAFEFVLKADDDSFARLDALLAELRAREPARRRRLYWGFFSGRGRVKPGGRWREAAWQLCDYYLPYALGGGYVLSADLVHYLRLSRDYLRAWHSEDVSLGAWLAPVDVQREHDPRFDTEYRSRGCSNQYLVTHKQSLEDMLEKHATLAREGRLCKREVQLRLSYVYDWSAPPSQCCQRREGIP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
131	N-linked (GlcNAc...) asparagine	29741879 37074911	G31986NC G00912UN G63381RX G25451PN G59626AS G36379GD	UniProt GlyGen GlyConnect
308		23584533	G57321FI	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Defective B3GALT6 causes EDSP2 and SEMDJL1	Homo sapiens
Glycosaminoglycan-protein linkage region biosynthesis	Homo sapiens

Disease

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0112198	spondyloepimetaphyseal dysplasia with joint laxity type 1	Alliance of Genome Resources
DOID:0050802	Ehlers-Danlos syndrome spondylodysplastic type 2	Alliance of Genome Resources