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Probable proton-coupled zinc antiporter SLC30A3

Summary

UniProt ID: Q99726
Gene Symbol: SLC30A3 ZNT3
Gene ID: 7781
Organism: Homo sapiens (human)

External Links

The Human Metabolome Database: HMDBP12038
The O-GlcNAc Database: Q99726
Re-Glyco: Q99726

Annotation

Keyword: 3D-structure Antiport Cytoplasmic vesicle Endosome Lysosome Metal-binding Proteomics identification Reference proteome Synaptosome Transmembrane helix Zinc transport

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
response to zinc ion	IBA	GO_REF
positive regulation of transport
zinc ion transmembrane transport	IDA	PMID
zinc ion transmembrane transport	IMP	PMID
zinc ion transmembrane transport	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

intercellular transport [inference]

cellular localization [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

zinc ion import into lysosome

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

zinc ion transmembrane transport

zinc ion import into organelle [inference]

vacuolar transmembrane transport [inference]

zinc ion import into lysosome

response to stimulus [inference]

response to chemical [inference]

response to metal ion [inference]

response to zinc ion

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

transition metal ion transport [inference]

zinc ion transport [inference]

zinc ion transmembrane transport

zinc ion import into organelle [inference]

monoatomic cation transmembrane transport [inference]

zinc ion transmembrane transport

zinc ion import into organelle [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

zinc ion transmembrane transport

zinc ion import into organelle [inference]

intercellular transport [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

zinc ion import into lysosome

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

zinc ion transmembrane transport

zinc ion import into organelle [inference]

vacuolar transmembrane transport [inference]

zinc ion import into lysosome

establishment of localization in cell [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

zinc ion import into lysosome

cellular localization [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

zinc ion import into lysosome

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

positive regulation of transport

positive regulation of biological process [inference]

positive regulation of transport

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	Reference
cytoplasm	IDA	PMID
lysosomal membrane	EXP	PMID
lysosomal membrane	IDA	PMID
lysosomal membrane	IEA	GO_REF
late endosome	IDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytoplasm

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

late endosome membrane

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

endosome membrane [inference]

late endosome membrane

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

neuron to neuron synapse [inference]

hippocampal mossy fiber to CA3 synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

axon [inference]

hippocampal mossy fiber

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

extracellular vesicle [inference]

microvesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

microvesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

microvesicle

Displaying **all 4** entries
GO Term	Evidence Code	Reference
zinc ion transmembrane transporter activity	IDA	PMID PMID PMID
zinc ion transmembrane transporter activity	IEA	GO_REF GO_REF
antiporter activity
metal ion binding

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

transition metal ion transmembrane transporter activity [inference]

zinc ion transmembrane transporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

antiporter activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MEPSPAAGGLETTRLVSPRDRGGAGGSLRLKSLFTEPSEPLPEESKPVEMPFHHCHRDPLPPPGLTPERLHARRQLYAACAVCFVFMAGEVVGGYLAHSLAIMTDAAHLLADVGSMMGSLFSLWLSTRPATRTMTFGWHRSETLGALASVVSLWMVTGILLYLAFVRLLHSDYHIEGGAMLLTASIAVCANLLMAFVLHQAGPPHSHGSRGAEYAPLEEGPEEPLPLGNTSVRAAFVHVLGDLLQSFGVLAASILIYFKPQYKAADPISTFLFSICALGSTAPTLRDVLRILMEGTPRNVGFEPVRDTLLSVPGVRATHELHLWALTLTYHVASAHLAIDSTADPEAVLAEASSRLYSRFGFSSCTLQVEQYQPEMAQCLRCQEPPQA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites