Zinc efflux and compartmentalization by the SLC30 family

Summary
Organism
Homo sapiens (human)
Reactome
R-HSA-435368
PubChem
R-HSA-435368
Description
  • The human SLC30 gene family of solute carriers is thought to participate in the homeostasis of zinc ions and facilitate zinc transport into specialized compartments of the cell such as endosomes, golgi network and synaptic vesicles. There are 10 members of this family, named ZnT1-10. ZnT4, ZnT9 and ZnT10 have no function determined as of yet (Palmiter RD and Huang L, 2004).
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Displaying all 3 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
Q8TAD4 Proton-coupled zinc antiporter SLC30A5
  • SLC30A5
  • UNQ863/PRO1879
  • ZNT5
  • ZNTL1
  • ZTL1
view
Q99726 Probable proton-coupled zinc antiporter SLC30A3
  • SLC30A3
  • ZNT3
view
Q9Y6M5 Proton-coupled zinc antiporter SLC30A1
  • SLC30A1
  • ZNT1
view

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026