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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Sclerostin
Summary
- UniProt ID
- Q9BQB4
- Gene Symbol
-
- SOST
- Organism
- Homo sapiens (human)
External Links
- PubChem
- Q9BQB4
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Heparin-binding
- Reference proteome
- Signal
- Wnt signaling pathway
- Gene Ontology (GO)
| GO Term |
|---|
| ossification |
| BMP signaling pathway |
| GO Term |
|---|
| extracellular region |
| extracellular space |
| Golgi apparatus |
| protein-containing complex |
| GO Term |
|---|
| heparin binding |
| carbohydrate binding |
| DNA-binding transcription factor binding |
| molecular function inhibitor activity |
| BMP binding |
Sequence
MQLPLALCLVCLLVHTAFRVVEGQGWQAFKNDATEIIPELGEYPEPPPELENNKTMNRAENGGRPPHHPFETKDVSEYSCRELHFTRYVTDGPCRSAKPVTELVCSGQCGPARLLPNAIGRGKWWRPSGPDFRCIPDRYRAQRVQLLCPGGEAPRARKVRLVASCKCKRLTRFHNQSELKDFGTEAARPQKGRKPRPRARSAKANQAELENAY
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Negative regulation of TCF-dependent signaling by WNT ligand antagonists | Homo sapiens |
| TCF dependent signaling in response to WNT | Homo sapiens |
