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Sialin
Summary
- UniProt ID
- Q9NRA2
- Gene Symbol
- SLC17A5
- Gene ID
- 26503
- Organism
- Homo sapiens (human)
External Links
- PubChem
- Q9NRA2
- The Human Metabolome Database
- HMDBP02797
- RaftProt
- Q9NRA2
- Re-Glyco
- Q9NRA2
Annotation
- Keyword
- 3D-structure Alternative splicing Amino-acid transport Cell membrane Cytoplasmic vesicle Disease variant Glycoprotein Lysosome Phosphoprotein Proteomics identification Reference proteome Symport Synapse Transmembrane helix
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| anion transport | ||
| monoatomic anion transport | ||
| amino acid transport |
|
|
| response to bacterium |
|
|
| sialic acid transport |
| GO Term | Evidence Code | Reference |
|---|---|---|
| lysosome | ||
| lysosomal membrane | ||
| lysosomal membrane | ||
| lysosomal membrane | ||
| lysosomal membrane |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| carbohydrate:proton symporter activity | ||
| glucuronate transmembrane transporter activity | ||
| sialic acid transmembrane transporter activity | ||
| sialic acid transmembrane transporter activity | ||
| sialic acid transmembrane transporter activity |
GO Hierarchy
Sequence
MRSPVRDLARNDGEESTDRTPLLPGAPRAEAAPVCCSARYNLAILAFFGFFIVYALRVNLSVALVDMVDSNTTLEDNRTSKACPEHSAPIKVHHNQTGKKYQWDAETQGWILGSFFYGYIITQIPGGYVASKIGGKMLLGFGILGTAVLTLFTPIAADLGVGPLIVLRALEGLGEGVTFPAMHAMWSSWAPPLERSKLLSISYAGAQLGTVISLPLSGIICYYMNWTYVFYFFGTIGIFWFLLWIWLVSDTPQKHKRISHYEKEYILSSLRNQLSSQKSVPWVPILKSLPLWAIVVAHFSYNWTFYTLLTLLPTYMKEILRFNVQENGFLSSLPYLGSWLCMILSGQAADNLRAKWNFSTLCVRRIFSLIGMIGPAVFLVAAGFIGCDYSLAVAFLTISTTLGGFCSSGFSINHLDIAPSYAGILLGITNTFATIPGMVGPVIAKSLTPDNTVGEWQTVFYIAAAINVFGAIFFTLFAKGEVQNWALNDHHGHRH
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Defective SLC17A5 causes Salla disease (SD) and ISSD | Homo sapiens |
| Hyaluronan degradation | Homo sapiens |
| Organic anion transport by SLC5/17/25 transporters | Homo sapiens |
| Sialic acid metabolism | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3659 | sialuria |
