GlyCosmos Portal

Submissions

Organic anion transport by SLC5/17/25 transporters

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-428643

PubChem

R-HSA-428643

Description

The SLC17 gene family encode proteins which are organic anion transporters. There are three distinct subfamilies within SLC17; vesicular glutamate transporters (VGLUT1-3 encoded by SLC17A7,6 and 8), type I Na+-coupled phosphate co-transporters (encoded by SLC17A1-4) and a proton-coupled sialic acid co-transporter (encoded by SLC17A5) (Reimer RJ and Edwards RH, 2004).

Two members of the SLC5 gene family encode carboxylate transporters, SMCT1 and SMCT2 (Ganapathy V et al, 2008).

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 4** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
Q02978	Mitochondrial 2-oxoglutarate/malate carrier protein	SLC20A4 SLC25A11	view
Q1EHB4	Sodium-coupled monocarboxylate transporter 2	SLC5A12 SMCT2	view
Q8N695	Sodium-coupled monocarboxylate transporter 1	AIT SLC5A8 SMCT SMCT1	view
Q9NRA2	Sialin	SLC17A5	view

If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".

About Release Notes Help Feedback

Click here to visit the beta site.