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Toll-like receptor 4

Summary

UniProt ID

Q9QUK6

Gene Symbol

Tlr4
Lps

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0007644
GlyGen: Q9QUK6
PubChem: Q9QUK6

Annotation

Keyword

3D-structure
Cell membrane
Cell projection
Disease variant
Disulfide bond
Endosome
Glycoprotein
Inflammatory response
Innate immunity
Leucine-rich repeat
NAD
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **41 - 50** of **101** in total

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GO Term
positive regulation of nitric oxide biosynthetic process
positive regulation of smooth muscle cell proliferation
positive regulation of lymphocyte proliferation
positive regulation of peptidyl-tyrosine phosphorylation
detection of temperature stimulus involved in sensory perception of pain
detection of mechanical stimulus involved in sensory perception of pain
positive regulation of nitric-oxide synthase biosynthetic process
positive regulation of macrophage cytokine production
response to fatty acid
positive regulation of cytokine production involved in inflammatory response

Displaying **all 10** entries
GO Term
lipopolysaccharide receptor complex
ruffle
phagocytic cup
endosome membrane
early endosome
external side of plasma membrane
cell surface
perinuclear region of cytoplasm
plasma membrane
receptor complex

Displaying **all 8** entries
GO Term
NAD+ nucleotidase, cyclic ADP-ribose generating
identical protein binding
protein heterodimerization activity
lipopolysaccharide binding
lipopolysaccharide immune receptor activity
phosphatidylinositol 3-kinase binding
transmembrane signaling receptor activity
signaling receptor binding

Annotation information from UniProt.

Sequence

MMPPWLLARTLIMALFFSCLTPGSLNPCIEVVPNITYQCMDQKLSKVPDDIPSSTKNIDLSFNPLKILKSYSFSNFSELQWLDLSRCEIETIEDKAWHGLHHLSNLILTGNPIQSFSPGSFSGLTSLENLVAVETKLASLESFPIGQLITLKKLNVAHNFIHSCKLPAYFSNLTNLVHVDLSYNYIQTITVNDLQFLRENPQVNLSLDMSLNPIDFIQDQAFQGIKLHELTLRGNFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIMEGLCDVTIDEFRLTYTNDFSDDIVKFHCLANVSAMSLAGVSIKYLEDVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLTLTMNKGSISFKKVALPSLSYLDLSRNALSFSGCCSYSDLGTNSLRHLDLSFNGAIIMSANFMGLEELQHLDFQHSTLKRVTEFSAFLSLEKLLYLDISYTNTKIDFDGIFLGLTSLNTLKMAGNSFKDNTLSNVFANTTNLTFLDLSKCQLEQISWGVFDTLHRLQLLNMSHNNLLFLDSSHYNQLYSLSTLDCSFNRIETSKGILQHFPKSLAFFNLTNNSVACICEHQKFLQWVKEQKQFLVNVEQMTCATPVEMNTSLVLDFNNSTCYMYKTIISVSVVSVIVVSTVAFLIYHFYFHLILIAGCKKYSRGESIYDAFVIYSSQNEDWVRNELVKNLEEGVPRFHLCLHYRDFIPGVAIAANIIQEGFHKSRKVIVVVSRHFIQSRWCIFEYEIAQTWQFLSSRSGIIFIVLEKVEKSLLRQQVELYRLLSRNTYLEWEDNPLGRHIFWRRLKNALLDGKASNPEQTAEEEQETATWT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 14 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
34	N-linked (GlcNAc...) asparagine	17803912		UniProt GlyGen
75	N-linked (GlcNAc...) asparagine	17803912		UniProt GlyGen
172	N-linked (GlcNAc...) asparagine	17803912		UniProt GlyGen
204	N-linked (GlcNAc...) asparagine	17803912		UniProt GlyGen
237	N-linked (GlcNAc...) asparagine	17803912	G62765YT	GlycoProtDB UniProt GlyGen
307	N-linked (GlcNAc...) asparagine	17803912		UniProt GlyGen
492	N-linked (GlcNAc...) asparagine	17803912		UniProt GlyGen
495	N-linked (GlcNAc...) asparagine			UniProt GlyGen
524	N-linked (GlcNAc...) asparagine	17803912		UniProt GlyGen
572	N-linked (GlcNAc...) asparagine	17803912	G50303LH	UniProt GlyGen