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Toll-like receptor 4

Summary

UniProt ID

Q9QUK6

Gene Symbol

Lps
Tlr4

Gene ID

21898

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0007644
GlyGen: Q9QUK6
PubChem: Q9QUK6
Re-Glyco: Q9QUK6

Annotation

Keyword

3D-structure
Cell membrane
Cell projection
Disease variant
Disulfide bond
Endosome
Glycoprotein
Inflammatory response
Innate immunity
Leucine-rich repeat
NAD
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 9** entries
GO Term
plasma membrane
receptor complex
early endosome
external side of plasma membrane
perinuclear region of cytoplasm
ruffle
endosome membrane
phagocytic cup
lipopolysaccharide receptor complex

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 89 in total

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GO Term
positive regulation of cytokine production involved in inflammatory response
gene expression
wound healing involved in inflammatory response
B cell proliferation involved in immune response
phagocytosis
inflammatory response
response to bacterium
positive regulation of platelet activation
positive regulation of gene expression
neurogenesis

Displaying **all 7** entries
GO Term
identical protein binding
protein heterodimerization activity
NAD+ nucleotidase, cyclic ADP-ribose generating
transmembrane signaling receptor activity
lipopolysaccharide binding
lipopolysaccharide immune receptor activity
signaling receptor binding

Annotation information from UniProt.

Sequence

MMPPWLLARTLIMALFFSCLTPGSLNPCIEVVPNITYQCMDQKLSKVPDDIPSSTKNIDLSFNPLKILKSYSFSNFSELQWLDLSRCEIETIEDKAWHGLHHLSNLILTGNPIQSFSPGSFSGLTSLENLVAVETKLASLESFPIGQLITLKKLNVAHNFIHSCKLPAYFSNLTNLVHVDLSYNYIQTITVNDLQFLRENPQVNLSLDMSLNPIDFIQDQAFQGIKLHELTLRGNFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIMEGLCDVTIDEFRLTYTNDFSDDIVKFHCLANVSAMSLAGVSIKYLEDVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLTLTMNKGSISFKKVALPSLSYLDLSRNALSFSGCCSYSDLGTNSLRHLDLSFNGAIIMSANFMGLEELQHLDFQHSTLKRVTEFSAFLSLEKLLYLDISYTNTKIDFDGIFLGLTSLNTLKMAGNSFKDNTLSNVFANTTNLTFLDLSKCQLEQISWGVFDTLHRLQLLNMSHNNLLFLDSSHYNQLYSLSTLDCSFNRIETSKGILQHFPKSLAFFNLTNNSVACICEHQKFLQWVKEQKQFLVNVEQMTCATPVEMNTSLVLDFNNSTCYMYKTIISVSVVSVIVVSTVAFLIYHFYFHLILIAGCKKYSRGESIYDAFVIYSSQNEDWVRNELVKNLEEGVPRFHLCLHYRDFIPGVAIAANIIQEGFHKSRKVIVVVSRHFIQSRWCIFEYEIAQTWQFLSSRSGIIFIVLEKVEKSLLRQQVELYRLLSRNTYLEWEDNPLGRHIFWRRLKNALLDGKASNPEQTAEEEQETATWT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 14 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
34	N-linked (GlcNAc...) asparagine	17803912		UniProt GlyGen
75	N-linked (GlcNAc...) asparagine	17803912		UniProt GlyGen
172	N-linked (GlcNAc...) asparagine	17803912		UniProt GlyGen
204	N-linked (GlcNAc...) asparagine	17803912		UniProt GlyGen
237	N-linked (GlcNAc...) asparagine	17803912	G62765YT	GlycoProtDB UniProt GlyGen
307	N-linked (GlcNAc...) asparagine	17803912		UniProt GlyGen
492	N-linked (GlcNAc...) asparagine	17803912		UniProt GlyGen
495	N-linked (GlcNAc...) asparagine			UniProt GlyGen
524	N-linked (GlcNAc...) asparagine	17803912		UniProt GlyGen
572	N-linked (GlcNAc...) asparagine	17803912	G50303LH	UniProt GlyGen