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Toll-like receptor 4

Summary

UniProt ID

Q9QUK6

Gene Symbol

Tlr4
Lps

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0007644
GlyGen: Q9QUK6
PubChem: Q9QUK6

Annotation

Keyword

3D-structure
Cell membrane
Cell projection
Disease variant
Disulfide bond
Endosome
Glycoprotein
Inflammatory response
Innate immunity
Leucine-rich repeat
NAD
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of **101** in total

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GO Term
microglial cell activation
wound healing involved in inflammatory response
B cell proliferation involved in immune response
nitric oxide production involved in inflammatory response
regulation of dendritic cell cytokine production
nitric oxide biosynthetic process
phagocytosis
inflammatory response
response to oxidative stress
response to bacterium

Displaying **all 10** entries
GO Term
plasma membrane
receptor complex
lipopolysaccharide receptor complex
ruffle
phagocytic cup
endosome membrane
early endosome
external side of plasma membrane
cell surface
perinuclear region of cytoplasm

Displaying **all 8** entries
GO Term
transmembrane signaling receptor activity
signaling receptor binding
NAD+ nucleotidase, cyclic ADP-ribose generating
identical protein binding
protein heterodimerization activity
lipopolysaccharide binding
lipopolysaccharide immune receptor activity
phosphatidylinositol 3-kinase binding

Annotation information from UniProt.

Sequence

MMPPWLLARTLIMALFFSCLTPGSLNPCIEVVPNITYQCMDQKLSKVPDDIPSSTKNIDLSFNPLKILKSYSFSNFSELQWLDLSRCEIETIEDKAWHGLHHLSNLILTGNPIQSFSPGSFSGLTSLENLVAVETKLASLESFPIGQLITLKKLNVAHNFIHSCKLPAYFSNLTNLVHVDLSYNYIQTITVNDLQFLRENPQVNLSLDMSLNPIDFIQDQAFQGIKLHELTLRGNFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIMEGLCDVTIDEFRLTYTNDFSDDIVKFHCLANVSAMSLAGVSIKYLEDVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLTLTMNKGSISFKKVALPSLSYLDLSRNALSFSGCCSYSDLGTNSLRHLDLSFNGAIIMSANFMGLEELQHLDFQHSTLKRVTEFSAFLSLEKLLYLDISYTNTKIDFDGIFLGLTSLNTLKMAGNSFKDNTLSNVFANTTNLTFLDLSKCQLEQISWGVFDTLHRLQLLNMSHNNLLFLDSSHYNQLYSLSTLDCSFNRIETSKGILQHFPKSLAFFNLTNNSVACICEHQKFLQWVKEQKQFLVNVEQMTCATPVEMNTSLVLDFNNSTCYMYKTIISVSVVSVIVVSTVAFLIYHFYFHLILIAGCKKYSRGESIYDAFVIYSSQNEDWVRNELVKNLEEGVPRFHLCLHYRDFIPGVAIAANIIQEGFHKSRKVIVVVSRHFIQSRWCIFEYEIAQTWQFLSSRSGIIFIVLEKVEKSLLRQQVELYRLLSRNTYLEWEDNPLGRHIFWRRLKNALLDGKASNPEQTAEEEQETATWT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **11 - 14** of 14 in total

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Position	Description	GlyTouCan ID	Source
575	N-linked (GlcNAc...) asparagine	G63703BK	UniProt GlyGen
613	N-linked (GlcNAc...) asparagine		UniProt GlyGen
621	N-linked (GlcNAc...) asparagine		UniProt GlyGen
622	N-linked (GlcNAc...) asparagine		UniProt GlyGen