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Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2

Summary

UniProt ID: Q9UJ37
Gene Symbol: ST6GALNAC2 SIAT7B SIATL1 STHM
Gene ID: 10610
Organism: Homo sapiens (human)

External Links

GlyGen: Q9UJ37
PubChem: Q9UJ37
The Human Metabolome Database: HMDBP11954
Re-Glyco: Q9UJ37

Annotation

Keyword: 3D-structure Disulfide bond Glycoprotein Glycosyltransferase Golgi apparatus Proteomics identification Reference proteome Signal-anchor Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
protein O-linked glycosylation	IDA	PMID
protein O-linked glycosylation	IBA	GO_REF
glycoprotein biosynthetic process	IDA	PMID
glycoprotein biosynthetic process	IEA	GO_REF
protein O-linked glycosylation via N-acetylgalactosamine	TAS	Reactome

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

protein O-linked glycosylation

protein O-linked glycosylation via N-acetylgalactosamine

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process

protein O-linked glycosylation

protein O-linked glycosylation via N-acetylgalactosamine

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

protein O-linked glycosylation

protein O-linked glycosylation via N-acetylgalactosamine

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

protein O-linked glycosylation

protein O-linked glycosylation via N-acetylgalactosamine

protein modification process [inference]

protein sialylation

macromolecule modification [inference]

protein modification process [inference]

protein sialylation

sialylation [inference]

protein sialylation

primary metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

protein O-linked glycosylation

protein O-linked glycosylation via N-acetylgalactosamine

protein modification process [inference]

protein sialylation

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

protein O-linked glycosylation

protein O-linked glycosylation via N-acetylgalactosamine

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process

protein O-linked glycosylation

protein O-linked glycosylation via N-acetylgalactosamine

viral process [inference]

viral protein processing

Displaying **all 2** entries
GO Term	Evidence Code	Reference
Golgi membrane	TAS	Reactome Reactome Reactome Reactome
Golgi membrane	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	Reference
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity	TAS	Reactome
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity	IDA	PMID PMID
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity	IBA	GO_REF
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity	IEA	GO_REF GO_REF GO_REF
sialyltransferase activity	TAS	Reactome Reactome Reactome

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

sialyltransferase activity

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MGLPRGSFFWLLLLLTAACSGLLFALYFSAVQRYPGPAAGARDTTSFEAFFQSKASNSWTGKGQACRHLLHLAIQRHPHFRGLFNLSIPVLLWGDLFTPALWDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEASASKFKLLHPDFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERKMKPLIFYANHDLSLEAALWRDLHKAGILQLYQR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
85	N-linked (GlcNAc...) asparagine	29251719		UniProt GlyGen
130	N-linked (GlcNAc...) asparagine	29251719	G39446WN	UniProt GlyGen
161	N-linked (GlcNAc...) asparagine	23090970 24190977 29251719		UniProt GlyGen
217		30459171	G43417UB	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
Maturation of protein 3a	Homo sapiens
Maturation of protein 3a	Homo sapiens
Maturation of spike protein	Homo sapiens
Sialic acid metabolism	Homo sapiens
Termination of O-glycan biosynthesis	Homo sapiens

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements