Maturation of protein 3a

Summary
Organism
Homo sapiens (human)
Reactome
R-HSA-9694719
PubChem
R-HSA-9694719
Description
  • This COVID-19 pathway has been created by a combination of computational inference from SARS-CoV-1 data (https://reactome.org/documentation/inferred-events) and manual curation, as described in the summation for the overall SARS-CoV-2 infection pathway.

    Protein 3a is associated with protein M and is found in the virion, although its function in the structure seems non-essential. 3a is O-glycosylated and forms a homotetramer with porin function (Oostra et al, 2006; Lu et al, 2006)
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026