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Glutathione hydrolase 5 proenzyme

Summary

UniProt ID: Q9Z2A9
Gene Symbol: Ggt5 Ggtla1
Gene ID: 23887
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0007854

GlyConnect

Gamma-glutamyltransferase 5

GlyGen

Q9Z2A9

PubChem

Q9Z2A9

Re-Glyco

Q9Z2A9

Annotation

Keyword: Acyltransferase Alternative splicing Glutathione biosynthesis Glycoprotein Leukotriene biosynthesis Protease Reference proteome Signal-anchor Transmembrane helix Zymogen

Gene Ontology (GO)

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	Reference
proteolysis	ISO	GO_REF
proteolysis	IEA	GO_REF
amino acid metabolic process	ISO	GO_REF
amino acid metabolic process	IEA	GO_REF
fatty acid metabolic process	ISO	GO_REF

GO Hierarchy

biological process

immune system process [inference]

leukocyte migration [inference]

mononuclear cell migration [inference]

lymphocyte migration

cellular process [inference]

metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

glutathione biosynthetic process

modified amino acid metabolic process [inference]

glutathione metabolic process [inference]

modified amino acid catabolic process [inference]

glutathione catabolic process

modified amino acid biosynthetic process [inference]

glutathione biosynthetic process

sulfur compound metabolic process [inference]

glutathione metabolic process [inference]

sulfur compound biosynthetic process [inference]

sulfur compound catabolic process [inference]

glutathione catabolic process

catabolic process [inference]

modified amino acid catabolic process [inference]

glutathione catabolic process

sulfur compound catabolic process [inference]

glutathione catabolic process

biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid derivative biosynthetic process [inference]

leukotriene D4 biosynthetic process

modified amino acid biosynthetic process [inference]

glutathione biosynthetic process

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

glutathione biosynthetic process

sulfur compound biosynthetic process [inference]

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

primary metabolic process [inference]

amino acid metabolic process

lipid metabolic process [inference]

fatty acid metabolic process

lipid biosynthetic process [inference]

fatty acid derivative biosynthetic process [inference]

leukotriene D4 biosynthetic process

fatty acid derivative metabolic process [inference]

fatty acid derivative biosynthetic process [inference]

leukotriene D4 biosynthetic process

protein metabolic process [inference]

proteolysis

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

leukotriene metabolic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

mononuclear cell migration [inference]

lymphocyte migration

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

Displaying **all 3** entries
GO Term	Evidence Code	Reference
plasma membrane	ISO	GO_REF
plasma membrane	IDA	PMID
plasma membrane	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	Reference
peptidyltransferase activity	ISO	GO_REF
peptidyltransferase activity	IEA	GO_REF
leukotriene-C(4) hydrolase activity	ISO	GO_REF
leukotriene-C(4) hydrolase activity	EXP	PMID PMID
leukotriene-C(4) hydrolase activity	IMP	PMID

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

aminoacyltransferase activity [inference]

peptidyltransferase activity

hydrolase activity [inference]

peptidase activity [inference]

omega peptidase activity [inference]

threonine-type peptidase activity [inference]

glutathione gamma-glutamate hydrolase

catalytic activity, acting on a protein [inference]

peptidyltransferase activity

peptidase activity [inference]

omega peptidase activity [inference]

threonine-type peptidase activity [inference]

glutathione gamma-glutamate hydrolase

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

catalytic activity, acting on a tRNA [inference]

peptidyltransferase activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MAWGHRATVCLVLLGVGLGLVIVVLAAVLSPRQASCGPGAFTRAAVAADSKICSDIGRAILQQRGSPVDAAIAALVCTGVVNPQSMGLGGGVVFTIYNASTGKVEIINARETVPASYDQGLLNQCKNVLPLGTGAQWIGVPGELRGYAEAHRRHGRLPWAQLFQPTIALLREGFRVPFILSQFLNNSILRPHLSASTLRQLFFNGTETLRSQDPFPWPALANTLETVAKEGAEVLYTGRLGRMLVEDIAKQGSLLTVQDLAAFQPEVVEPLEMPLGNYTLYSPPPPAGGAILSFILNVLKGFNFSAETVARPGGEVNMYHHLVETLKFAVGQRWRLWDPSSHPGIQNISRDLLREDLAQRIRQQIDGRGDHHQLSHYNLTGVRGNRMGTSHVSVLGEDGSAVAATSTINTPFGAMVYSPRTGILLNNELLDLCWRHMPTSPITPPPVPGERPPSSMVPSILVNKGQGSKLVIGGAGGELIISAVAQTIMNKLWLGFDLTEAIASPILHVNSKGHVEYEPKFNQEVQKGLQDRGQIQSQSQRPVFLNAVQAVFQEGPCVYAASDLRKAGKASGY

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
98	N-linked (GlcNAc...) asparagine		G35253PZ	UniProt GlyGen
185	N-linked (GlcNAc...) asparagine		G41071NU	UniProt GlyGen
204	N-linked (GlcNAc...) asparagine		G62765YT	GlycoProtDB UniProt GlyGen
277	N-linked (GlcNAc...) asparagine			UniProt GlyGen
303	N-linked (GlcNAc...) asparagine	30899004	G72747WU G06110VR	GlycoProtDB UniProt GlyGen GlyConnect
347	N-linked (GlcNAc...) asparagine		G80920RR	GlycoProtDB UniProt GlyGen
378	N-linked (GlcNAc...) asparagine		G15664MX	GlycoProtDB UniProt GlyGen
443				GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
APAP ADME	Mus musculus
Aflatoxin activation and detoxification	Mus musculus
Glutathione synthesis and recycling	Mus musculus
Synthesis of Leukotrienes (LT) and Eoxins (EX)	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

Annotation

International Collaboration

Acknowledgements