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Glutamate receptor 3

Summary

UniProt ID: Q9Z2W9
Gene Symbol: Gria3 GluA3 Glur3 Kiaa4184
Gene ID: 53623
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0007864

GlyConnect

Glutamate receptor 3

GlyGen

Q9Z2W9

PubChem

Q9Z2W9

The O-GlcNAc Database

Q9Z2W9

O-GlcNAcAtlas

Q9Z2W9

Re-Glyco

Q9Z2W9

Annotation

Keyword: 3D-structure Alternative splicing Cell membrane Disulfide bond Glycoprotein Ligand-gated ion channel Palmitate Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Signal Transmembrane helix

Gene Ontology (GO)

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GO Term	Evidence Code	Reference
regulation of receptor recycling	ISO	GO_REF
synaptic transmission, glutamatergic	IBA	GO_REF
modulation of chemical synaptic transmission	IBA	GO_REF
protein homotetramerization	ISS	GO_REF
protein homotetramerization	ISO	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, glutamatergic

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotetramerization

protein tetramerization [inference]

protein heterooligomerization [inference]

protein heterotetramerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotetramerization

protein tetramerization [inference]

protein heterooligomerization [inference]

protein heterotetramerization

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of receptor recycling

positive regulation of signaling [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of synaptic plasticity [inference]

long-term synaptic potentiation

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, glutamatergic

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

regulation of cellular process [inference]

regulation of cell communication [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of synaptic plasticity [inference]

long-term synaptic potentiation

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

regulation of metabolic process [inference]

regulation of macromolecule metabolic process [inference]

regulation of receptor recycling

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

regulation of biological quality [inference]

regulation of synaptic plasticity [inference]

long-term synaptic potentiation

Displaying entries **1 - 5** of 34 in total

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GO Term	Evidence Code	Reference
plasma membrane	ISS	GO_REF
plasma membrane	ISO	GO_REF
plasma membrane	IEA	GO_REF
postsynaptic density	ISO	GO_REF
membrane	IDA	PMID

GO Hierarchy

cellular component

protein-containing complex

signaling receptor complex [inference]

plasma membrane signaling receptor complex [inference]

neurotransmitter receptor complex [inference]

ionotropic glutamate receptor complex [inference]

AMPA glutamate receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

neurotransmitter receptor complex [inference]

ionotropic glutamate receptor complex [inference]

AMPA glutamate receptor complex

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

ionotropic glutamate receptor complex [inference]

AMPA glutamate receptor complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

ionotropic glutamate receptor complex [inference]

AMPA glutamate receptor complex

cellular anatomical structure [inference]

membrane

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic specialization membrane [inference]

postsynaptic density membrane

cell junction [inference]

synapse [inference]

excitatory synapse [inference]

parallel fiber to Purkinje cell synapse

glutamatergic synapse

neuron to neuron synapse [inference]

asymmetric synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

neuron spine [inference]

dendritic spine

organelle [inference]

postsynaptic specialization [inference]

postsynaptic density

cell body [inference]

neuronal cell body

presynapse [inference]

terminal bouton

postsynapse [inference]

dendritic spine

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	Reference
amyloid-beta binding	ISO	GO_REF
glutamate-gated receptor activity	ISS	GO_REF
glutamate-gated receptor activity	ISO	GO_REF GO_REF
AMPA glutamate receptor activity	ISS	GO_REF
AMPA glutamate receptor activity	ISO	GO_REF GO_REF

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

calcium channel activity [inference]

ligand-gated calcium channel activity

glutamate-gated calcium ion channel activity

ligand-gated monoatomic cation channel activity [inference]

ligand-gated calcium channel activity

glutamate-gated calcium ion channel activity

ligand-gated monoatomic ion channel activity [inference]

extracellular ligand-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity [inference]

glutamate-gated receptor activity

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

ligand-gated monoatomic cation channel activity [inference]

ligand-gated calcium channel activity

glutamate-gated calcium ion channel activity

ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

calcium channel activity [inference]

ligand-gated calcium channel activity

glutamate-gated calcium ion channel activity

ligand-gated monoatomic cation channel activity [inference]

ligand-gated calcium channel activity

glutamate-gated calcium ion channel activity

metal ion transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity [inference]

ligand-gated calcium channel activity

glutamate-gated calcium ion channel activity

amino acid transmembrane transporter activity [inference]

glutamate-gated receptor activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

calcium channel activity [inference]

ligand-gated calcium channel activity

glutamate-gated calcium ion channel activity

ligand-gated monoatomic cation channel activity [inference]

ligand-gated calcium channel activity

glutamate-gated calcium ion channel activity

ligand-gated monoatomic ion channel activity [inference]

extracellular ligand-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity [inference]

glutamate-gated receptor activity

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

ligand-gated monoatomic cation channel activity [inference]

ligand-gated calcium channel activity

glutamate-gated calcium ion channel activity

ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

extracellular ligand-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity [inference]

glutamate-gated receptor activity

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

ligand-gated monoatomic cation channel activity [inference]

ligand-gated calcium channel activity

glutamate-gated calcium ion channel activity

ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

transmitter-gated channel activity [inference]

transmitter-gated monoatomic ion channel activity [inference]

glutamate-gated receptor activity

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

carboxylic acid transmembrane transporter activity [inference]

glutamate-gated receptor activity

binding [inference]

peptide binding [inference]

amyloid-beta binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

glutamate receptor activity [inference]

glutamate-gated receptor activity

neurotransmitter receptor activity [inference]

transmitter-gated channel activity [inference]

transmitter-gated monoatomic ion channel activity [inference]

glutamate-gated receptor activity

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MGQSVLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQFVIQMRPALKGAILSLLGYYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTARSVGNIKDIQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDIVLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWWYDKGECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMKLTKNTQNFKPAPATNTQNYATYREGYNVYGTESVKI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
57	N-linked (GlcNAc...) asparagine		G50282JC	UniProt GlyGen
120				GlyGen
260	N-linked (GlcNAc...) asparagine	30899004	G48584BU G31916IQ G14260UH G83633GK G64527OM G05724UK G39188ZX	GlycoProtDB UniProt GlyGen GlyConnect
374	N-linked (GlcNAc...) asparagine	30899004	G64527OM G39188ZX G41247ZX G06110VR	GlycoProtDB UniProt GlyGen GlyConnect
403		33300544 34678516 40885482	G49108TO	The O-GlcNAc Database
409	N-linked (GlcNAc...) asparagine			GlycoProtDB UniProt GlyGen
416	N-linked (GlcNAc...) asparagine		G93910IH	GlycoProtDB UniProt GlyGen
883			G49108TO	GlyGen