Klotho

Summary
UniProt ID
Q9Z2Y9
Gene Symbol
  • Kl
Organism
Rattus norvegicus (Norway rat)
External Links
PubChem
Q9Z2Y9
Annotation
Sequence
MPARAPPRRLPRLLLLRLLSLHLLLLTLRARCLSAEPGQGAQTWARFARPPVPEASGLLHDTFPDGFLWAVGSAAYQTEGGWRQHGKGASIWDTFTHHPRAIPEDSPIVMAPSGAPLPPLPSTGDVASDSYNNVYRDTEGLRELGVTHYRFSISWARVLPNGTAGTPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQDTYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGVRGSSRLGYLVAHNLLLAHAKVWRLYNTSFRPTQGGRVSIALGSHWITPRRMTDYHIRECQKSLDFVLGWFAKPIFIDGDYPKSMKNNLSSLLPDFTESEKRFIRGTADFFALSFGPTLSFQLLDPSMKFRQLESPSLRQLLSWIDLEYNHPQIFIVENGWFVSGTTRRDDAKYMYYLKKFIMESLKAIRLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKELLPKSSALFYQKLIENNGFPPLPENQPLEGTFPCDFAWGVVDNYIQVDPTLSQFTDPNVYLWDVHHSKRLIKVDGVVAKKRKPYCVDFSAIRPQITLLREMRVTHFRFSLDWALILPLGNQTQVNRTVLHFYRCMVSELVHANITPVVALWQPATPHQGLPHALAKHGAWENPHTALAFADYANLCFEELGHWVKFWITINEPNSRNMTYRAGHHLLKAHALAWHLYDDKFRAAQKGKISIALQVDWIEPACPFSQKDKEVAERVLEFDVGWLAEPIFGSGDYPHVMREWLNQKNNFLLPYFTEDEKKLIRGSFDFLALSHYTTILVDWEKEDPIKYNDYLEVQEMTDITWLNSPNQVAVVPWGLRKALNWLRFKYGDLPMFVTANGIDDDPHAEQDSLRMYYIKNYVNEALKAYVLDGINLCGYFAYSLSDRSVPKSGFYRYAANQFEPKPSIKHYRKIIDNNGFLGSGTLGRFCPEEYTVCTGCGFFQTRKSLLAFISFLVFAFVTSLALIYYYSKKGRRRYK
Glycosylation Sites
Displaying all 6 entries
Position Description PubMed ID GlyTouCan ID Source
161 N-linked (GlcNAc...) asparagine
285 N-linked (GlcNAc...) asparagine
346 N-linked (GlcNAc...) asparagine
609 N-linked (GlcNAc...) asparagine
614 N-linked (GlcNAc...) asparagine
696 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying entries 1 - 10 of 11 in total
Pathway Name Organism
Downstream signaling of activated FGFR1 Rattus norvegicus
FGFR1c and Klotho ligand binding and activation Rattus norvegicus
FRS-mediated FGFR1 signaling Rattus norvegicus
Negative regulation of FGFR1 signaling Rattus norvegicus
PI-3K cascade:FGFR1 Rattus norvegicus
PI3K Cascade Rattus norvegicus
PI3K/AKT Signaling Rattus norvegicus
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Rattus norvegicus
Phospholipase C-mediated cascade: FGFR1 Rattus norvegicus
RAF/MAP kinase cascade Rattus norvegicus

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024