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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase
Summary
- UniProt ID
- Q8N0V5
- Gene Symbol
-
- GCNT2
- GCNT5
- II
- NACGT1
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0012385
- GlyGen
- Q8N0V5
- PubChem
- Q8N0V5
- The Human Metabolome Database
- HMDBP11751
Annotation
- Keyword
-
- Alternative splicing
- Cataract
- Disease variant
- Glycoprotein
- Glycosyltransferase
- Golgi apparatus
- Reference proteome
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of cell migration |
| positive regulation of epithelial to mesenchymal transition |
| positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| GO Term |
|---|
| Golgi apparatus |
| membrane |
| Golgi membrane |
| GO Term |
|---|
| acetylglucosaminyltransferase activity |
| N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity |
Sequence
MMGSWKHCLFSASLISALIFVFVYNTELWENKRFLRAALSNASLLAEACHQIFEGKVFYPTENALKTTLDEATCYEYMVRSHYVTETLSEEEAGFPLAYTVTIHKDFGTFERLFRAIYMPQNVYCVHLDQKATDAFKGAVKQLLSCFPNAFLASKKESVVYGGISRLQADLNCLEDLVASEVPWKYVINTCGQDFPLKTNREIVQYLKGFKGKNITPGVLPPDHAVGRTKYVHQELLNHKNSYVIKTTKLKTPPPHDMVIYFGTAYVALTRDFANFVLQDQLALDLLSWSKDTYSPDEHFWVTLNRIPGVPGSMPNASWTGNLRAIKWSDMEDRHGGCHGHYVHGICIYGNGDLKWLVNSPSLFANKFELNTYPLTVECLELRHRERTLNQSETAIQPSWYF
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1612 | breast cancer | |
| DOID:162 | cancer | |
| DOID:1909 | melanoma | |
| DOID:219 | colon cancer | |
| DOID:235 | colonic benign neoplasm | |
| DOID:2893 | cervix carcinoma | |
| DOID:3121 | gallbladder cancer | |
| DOID:3459 | breast carcinoma | |
| DOID:3702 | cervical adenocarcinoma | |
| DOID:3748 | esophagus squamous cell carcinoma |
