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Dolichol-phosphate mannosyltransferase subunit 1

Summary

GlyCosmos Lectin

GL_004645

Lectin Name Aliases

DPM synthase subunit 1
Dolichol-phosphate mannose synthase subunit 1
Dolichyl-phosphate beta-D-mannosyltransferase subunit 1
MPD synthase subunit 1
Mannose-P-dolichol synthase subunit 1

Organism

Homo sapiens (human)

External Links

UniProt: O60762

Annotation

Keyword: Acetylation Congenital disorder of glycosylation Congenital muscular dystrophy Disease variant Dystroglycanopathy Endoplasmic reticulum Glycosyltransferase Magnesium Manganese Metal-binding Phosphoprotein Proteomics identification Reference proteome

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	Reference
dolichol-linked oligosaccharide biosynthetic process	TAS	Reactome
dolichol-linked oligosaccharide biosynthetic process	IBA	GO_REF
GPI anchor biosynthetic process	IDA	PMID PMID
GPI anchor biosynthetic process	IGI	PMID
GPI anchor biosynthetic process	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

phospholipid biosynthetic process [inference]

dolichyl monophosphate biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

dolichol phosphate mannose biosynthetic process

nucleoside phosphate metabolic process [inference]

nucleotide-sugar metabolic process [inference]

GDP-mannose metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

phospholipid biosynthetic process [inference]

dolichyl monophosphate biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

dolichol phosphate mannose biosynthetic process

nucleoside phosphate metabolic process [inference]

nucleotide-sugar metabolic process [inference]

GDP-mannose metabolic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

dolichyl monophosphate biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

dolichol phosphate mannose biosynthetic process

biosynthetic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

dolichol phosphate mannose biosynthetic process

phospholipid biosynthetic process [inference]

dolichyl monophosphate biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

dolichol phosphate mannose biosynthetic process

glycolipid biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via mannose

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

dolichyl monophosphate biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

dolichol phosphate mannose biosynthetic process

carbohydrate derivative biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via mannose

glycolipid biosynthetic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via mannose

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via mannose

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide-sugar metabolic process [inference]

GDP-mannose metabolic process

lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

phospholipid biosynthetic process [inference]

dolichyl monophosphate biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

dolichol phosphate mannose biosynthetic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

terpenoid biosynthetic process [inference]

dolichol phosphate mannose biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

dolichol phosphate mannose biosynthetic process

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

dolichol phosphate mannose biosynthetic process

phospholipid biosynthetic process [inference]

dolichyl monophosphate biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

dolichol phosphate mannose biosynthetic process

glycolipid biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor biosynthetic process

glycolipid biosynthetic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via mannose

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide-sugar metabolic process [inference]

GDP-mannose metabolic process

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via mannose

nucleotide-sugar metabolic process [inference]

GDP-mannose metabolic process

carbohydrate derivative biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via mannose

glycolipid biosynthetic process [inference]

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor biosynthetic process

glycolipid biosynthetic process [inference]

response to stimulus [inference]

response to abiotic stimulus [inference]

response to oxygen levels

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	Reference
nucleus	HDA	PMID
endoplasmic reticulum	IDA	PMID
endoplasmic reticulum	IEA	GO_REF
endoplasmic reticulum membrane	NAS	PMID
endoplasmic reticulum membrane	TAS	Reactome Reactome Reactome Reactome

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

mannosyltransferase complex [inference]

dolichol-phosphate-mannose synthase complex

catalytic complex [inference]

transferase complex [inference]

mannosyltransferase complex [inference]

dolichol-phosphate-mannose synthase complex

cellular anatomical structure [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
dolichyl-phosphate beta-D-mannosyltransferase activity	EXP	PMID
dolichyl-phosphate beta-D-mannosyltransferase activity	IDA	PMID PMID
dolichyl-phosphate beta-D-mannosyltransferase activity	IGI	PMID
dolichyl-phosphate beta-D-mannosyltransferase activity	IBA	GO_REF
dolichyl-phosphate beta-D-mannosyltransferase activity	IEA	GO_REF GO_REF GO_REF GO_REF GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

mannosyltransferase activity [inference]

dolichyl-phosphate beta-D-mannosyltransferase activity

binding [inference]

carbohydrate binding [inference]

monosaccharide binding [inference]

D-mannose binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

alcohol binding

monosaccharide binding [inference]

D-mannose binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Pathway

Displaying **all 5** entries
Pathway Name	Organism
Defective DPM1 causes CDG-1e	Homo sapiens
Defective DPM2 causes CDG-1u	Homo sapiens
Defective DPM3 causes CDG-1o	Homo sapiens
Maturation of DENV proteins	Homo sapiens
Synthesis of dolichyl-phosphate mannose	Homo sapiens