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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source ▲ | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Chlamydia trachomatis | Unknown | Pentosan polysulfate (PP) | Polysaccharides | HeLa cells | Binding | 9420059 | |
| Chlamydia trachomatis | Unknown | Dextran sulfate | Polysaccharides | HeLa cells | Binding | 9420059 | |
| Chlamydia trachomatis | Unknown | NAC-heparin (non-anticoagulant heparin) | Glycosaminoglycans | HeLa cells | Binding | 9420059 | |
| Shigella dysenteriae | B subunit | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | HeLa cells, Rabbit jejunul mucosa | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3519828 |
| Lactobacillus johnsonii | Unknown | GM3(NeuGc) | Monosialoglycosphingolipids | Horse erythrocytes | NeuGc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11087711 |
| Influenza virus | Unknown | Alpha-1-acid glycoprotein (AGP) | Glycoproteins | Human | Not Binding | 1740131 | |
| Human immunodeficiency virus | Unknown | N-acetyl-b-maltoheptaosylamine sulfate (SM) | Oligosaccharides | Human T cells | Binding | 9420059 | |
| Human immunodeficiency virus | Unknown | Pentosan polysulfate (PP) | Polysaccharides | Human T cells | Binding | 9420059 | |
| Human immunodeficiency virus | Unknown | Dextran sulfate | Polysaccharides | Human T cells | Binding | 9420059 | |
| Human immunodeficiency virus | Unknown | NAC-heparin (non-anticoagulant heparin) | Glycosaminoglycans | Human T cells | Binding | 9420059 | |
| Human immunodeficiency virus | gp120 | Sulfatide (CSE) | Sulfoglycosphingolipids | Human U373-MG glioma and SK-N-MC neuroblastoma cells, Human colon epithelial HT29 cells | HSO3(-3)Gal(b1-1)Cer | Binding | 15973004 |
| Human immunodeficiency virus | gp120 | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Human U373-MG glioma and SK-N-MC neuroblastoma cells, Human colon epithelial HT29 cells | Gal(b1-1)Cer | Binding | 15973004 |
| Bordetella pertussis | PT (subunit S3 of B oligomer) | Gangliosides | Sialoglycosphingolipids | Human alveolar macrophages | Binding | 1729677 | |
| Bordetella pertussis | Pertussis toxin | Gangliosides | Sialoglycosphingolipids | Human alveolar macrophages | Binding | 1729677 | |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Sialyl Lewis a (SLea) (GSL) | Monosialoglycosphingolipids | Human bile bladder tumor | NeuAc(a2-3)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Actinomyces naeslundii | Unknown | GD1b | Disialoglycosphingolipids | Human brain | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Actinomyces naeslundii | Unknown | GM1 | Monosialoglycosphingolipids | Human brain | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Actinomyces viscosus | Unknown | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Human brain | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Actinomyces naeslundii | Unknown | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Human brain | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Actinomyces viscosus | Unknown | GD1a | Disialoglycosphingolipids | Human brain | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | GD1a | Disialoglycosphingolipids | Human brain | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Actinomyces naeslundii | Unknown | GD1a | Disialoglycosphingolipids | Human brain | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | GM3(NeuAc) | Monosialoglycosphingolipids | Human brain | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
| Escherichia coli | F1C | GM3(NeuAc) | Monosialoglycosphingolipids | Human brain | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Actinomyces viscosus | Unknown | GD1b | Disialoglycosphingolipids | Human brain | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
