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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source ▼ | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Fucosyl Asialo GM1 | Oligoglycosylceramides | Mouse intestine | Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9228091 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Sulfo-gangliotetraosylceramide (Sulfo-GgO4) | Sulfoglycosphingolipids | Mouse intestine | HSO3(-3)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9228091 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Mouse intestine | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9228091 |
| Lactobacillus johnsonii | Unknown | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Mouse feces | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11087711 |
| Escherichia coli | F1C | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Mouse feces | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Clostridium difficile | Toxin A | α-Gal on Fab of IgA(κ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Clostridium difficile | Toxin A | α-Gal on Fab of IgM(λ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Clostridium difficile | Unknown | α-Gal on Fab of IgA(κ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Clostridium difficile | Unknown | α-Gal on Fab of IgM(λ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Clostridium difficile | Toxin A | β-Gal on Fab of IgG3(λ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Clostridium difficile | Unknown | β-Gal on Fab of IgG3(λ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Actinomyces viscosus | Unknown | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Most tissues | Gal(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces naeslundii | Unknown | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Most tissues | Gal(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces viscosus | Unknown | Glucosylceramide | Monoglycosylceramides | Most tissues | Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces naeslundii | Unknown | Glucosylceramide | Monoglycosylceramides | Most tissues | Glc(b1-1)Cer | Not Binding | 2358461 |
| Reovirus | Unknown | Sialic acid (α2,6) | Saccharides | Most organs including the central nervous system/heart/liver | NeuAc(a2-6) | Binding | 18216114 |
| Reovirus | Unknown | Sialic acid (α2,3) | Saccharides | Most organs including the central nervous system/heart/liver | NeuAc(a2-3) | Binding | 18216114 |
| Reovirus | Unknown | Junctional adhesion molecule A (JAM-A) | Glycoproteins | Most organs including the central nervous system/heart/liver | Binding | 18216114 | |
| Bordetella pertussis | FimD | VLA-5 (very late activation antigen 5) | Glycoproteins | Monocytes | Binding | 11348687 | |
| Plasmodium falciparum | Unknown | Neuraminidase-insensitive, trypsin sensitive carbohydrate ligand | Glycoconjugates | Molecules on the erythrocyte membrane (other than glycophorins A and B) | Binding | 3308959 | |
| Rabbit fibroma virus | Unknown | Heparan sulfate | Glycosaminoglycans | Mammalian cell surface | Binding | 9445060 | |
| Rabbit fibroma virus | Unknown | Heparan sulfate | Glycosaminoglycans | Mammalian cell surface | Binding | 9445060 | |
| Rabbit fibroma virus | Unknown | Heparan sulfate | Glycosaminoglycans | Mammalian cell surface | Binding | 9445060 | |
| Rabbit fibroma virus | Unknown | Heparan sulfate | Glycosaminoglycans | Mammalian cell surface | Binding | 9445060 | |
| Vaccinia virus | A27L proteins | Heparan sulfate | Glycosaminoglycans | Mammalian cell surface | Binding | 9445060 |
