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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▼ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Helicobacter pylori | SabA (sialic acid-binding adhesin) | Fucosylated Lewis b (Leb) histoblood group antigens | Oligosaccharides | Mucosal surface of the gastric epithelium | Binding | 12640357 | |
| Norovirus | Unknown | Blood group O antigen | Oligosaccharides | Human saliva | Binding | 16707048 | |
| Helicobacter pylori | BabA (blood group antigen binding adhesin) | Fucosylated Lewis b (Leb) histoblood group antigens | Oligosaccharides | Human gastric epithelium | Binding | 9430586 | |
| Human immunodeficiency virus | Unknown | N-acetyl-b-maltoheptaosylamine sulfate (SM) | Oligosaccharides | Human T cells | Binding | 9420059 | |
| Chlamydia trachomatis | Unknown | N-acetyl-b-maltoheptaosylamine sulfate (SM) | Oligosaccharides | HeLa cells | Binding | 9420059 | |
| Herpes simplex virus | Unknown | N-acetyl-b-maltoheptaosylamine sulfate (SM) | Oligosaccharides | Human cervical cells | Binding | 9420059 | |
| Pseudomonas aeruginosa | PA-IIL | Blood group Lewis b (Leb) antigen | Oligosaccharides | Binding | 16762477 | ||
| Helicobacter pylori | Leb-binding adhesin | Fucosylated Lewis b (Leb) histoblood group antigens | Oligosaccharides | Binding | 10341176 | ||
| Norovirus | Unknown | Blood group Lewis b (Leb) antigen | Oligosaccharides | Binding | 18701592 | ||
| Helicobacter pylori | Unknown | Blood group antigens | Oligosaccharides | Binding | 16088272 | ||
| Helicobacter pylori | Unknown | Blood group Lewis b (Leb) antigen | Oligosaccharides | Binding | 16088272 | ||
| Helicobacter pylori | BabA (blood group antigen binding adhesin) | Blood group Lewis b (Leb) antigen | Oligosaccharides | Binding | 15273394 | ||
| Helicobacter pylori | BabA (blood group antigen binding adhesin) | Blood group Lewis b (Leb) antigen | Oligosaccharides | Binding | 15973004 | ||
| Helicobacter pylori | Adhesins | Blood group Lewis b (Leb) antigen | Oligosaccharides | Binding | 8018146 | ||
| Helicobacter pylori | Lectin-hemagglutinin adhesins | Blood group Lewis b (Leb) antigen | Oligosaccharides | Binding | 12704182 | ||
| Lactobacillus johnsonii | Unknown | Blood group Lewis b (Leb) antigen | Oligosaccharides | Binding | 11087711 | ||
| Staphylococcus aureus | SSL5 | Sialyl Lewis x (SLex) antigen | Oligosaccharides | (broad range) | NeuAc(a2-3)Gal(b1-4) | Binding | 18809496 |
| Staphylococcus aureus | SSL11 | Sialyl Lewis x (SLex) antigen | Oligosaccharides | (broad range) | NeuAc(a2-3)Gal(b1-4) | Binding | 18809496 |
| Helicobacter pylori | SabA (sialic acid-binding adhesin) | Sialyl Lewis x (SLex) antigen | Oligosaccharides | Gastric epithelial progenitors (GEPs) | NeuAc(a2-3)Gal(b1-4) | Binding | 16406776 |
| Helicobacter pylori | HpaA | Sialyl Lewis x (SLex) antigen | Oligosaccharides | Gastric epithelial progenitors (GEPs) | NeuAc(a2-3)Gal(b1-4) | Binding | 16406776 |
| Helicobacter pylori | HP0721 | Sialyl Lewis x (SLex) antigen | Oligosaccharides | Gastric epithelial progenitors (GEPs) | NeuAc(a2-3)Gal(b1-4) | Binding | 16406776 |
| Polyoma virus | Unknown | Sialylated oligosaccharides | Oligosaccharides | Erythrocytes | NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc | Binding | 6316632 |
| Influenza virus | Residues 226 (leucine) and 228 (serine) | Sialic acid α2,6Galβ1,4GalNAc | Oligosaccharides | Human isolates | NeuAc(a2-6)Gal(b1-4)GalNAc | Binding | 7975212 |
| Haemophilus influenzae | Unknown | Pentasaccharide | Oligosaccharides | Respiratory tract | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 16564136 |
| Streptococcus pneumoniae | Unknown | Pentasaccharide | Oligosaccharides | Respiratory tract | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 16564136 |
