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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID ▼ |
|---|---|---|---|---|---|---|---|
| Parvovirus | Unknown | O-linked alpha 2,3 neuraminic acid on glycophorin A (GPA) | Glycoproteins | Human erythrocytes | Binding | 15750863 | |
| Helicobacter pylori | SabA (sialic acid-binding adhesin) | Sialic acid | Monosaccharides | Human neutrophils | Binding | 15689619 | |
| Adenovirus | Fibre proteins | HSA glycoconjugates | Glycoproteins | Human corneal epithelial(HEC) cells | Binding | 15678425 | |
| Helicobacter pylori | Unknown | Sialyl-3-Paragloboside (S-3-PG; α2,3-sialylparagloboside) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 15659615 | |
| Helicobacter pylori | Unknown | Sialyl Lewis x (SLex) antigen (d18:1,18:0) | Oligosaccharides | NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b | Binding | 15659615 | |
| Helicobacter pylori | Unknown | Mono-N-propionylated S-3-PG (paragloboside) | Glycosphingolipids | Binding | 15659615 | ||
| Helicobacter pylori | Unknown | Mono-de-N-acetylated S-3-PG (paragloboside) | Glycosphingolipids | Binding | 15659615 | ||
| Streptococcus pneumoniae | CTB-PsaA pentamers | GM1 | Monosialoglycosphingolipids | Serum, Saliva, Nasal/bronchial wash samples | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 15358234 |
| Sporothrix schenckii | Yeast cells and hyphae | Fibronectin | Glycoproteins | Extracellular matrix (ECM) | Binding | 15351036 | |
| Sporothrix schenckii | Yeast cells and hyphae | Laminin | Glycoproteins | Extracellular matrix (ECM) | Binding | 15351036 | |
| Entamoeba histolytica | Transmembrane heavy subunit (Hgl; 170-kDa) disulfide linked to a GPI-anchored light subunit (Lgl; 31-to 35-kDa). | N-Acetylgalactosamine | Monosaccharides | Intestinal cells | GalNAc | Binding | 15322032 |
| Entamoeba histolytica | Transmembrane heavy subunit (Hgl; 170-kDa) disulfide linked to a GPI-anchored light subunit (Lgl; 31-to 35-kDa). | Galactose | Monosaccharides | Intestinal cells | Gal | Binding | 15322032 |
| Entamoeba histolytica | Raft-like plasma membrane domains | N-Acetylgalactosamine | Monosaccharides | Intestinal cells | GalNAc | Binding | 15322032 |
| Entamoeba histolytica | Raft-like plasma membrane domains | Galactose | Monosaccharides | Intestinal cells | Gal | Binding | 15322032 |
| Entamoeba histolytica | Transmembrane heavy subunit (Hgl; 170-kDa) disulfide linked to a GPI-anchored light subunit (Lgl; 31-to 35-kDa). | β-2 and β-7 integrins | Glycoproteins | Intestinal cells | Binding | 15322032 | |
| Entamoeba histolytica | Raft-like plasma membrane domains | β-2 and β-7 integrins | Glycoproteins | Intestinal cells | Binding | 15322032 | |
| Equine rhinitis A virus | Viral protein | NeuAc/GlcNAc/(GlcNAc)n side chains of WGA-binding glycoproteins | Glycoproteins | Feline kidney(CRFK)/Equine fetal kidney(EFK)/Mouse(McCoy)/Rabbit kidney(RK-13) | NeuAc/GlcNAc/(GlcNAc)n | Binding | 15302947 |
| Equine rhinitis A virus | Viral protein | NeuAcα2,3-Gal/GalNAc side chains of MAA-binding glycoproteins | Glycoproteins | Feline kidney(CRFK)/Equine fetal kidney(EFK)/Mouse(McCoy)/Rabbit kidney(RK-13) | NeuAc(a2-3)Gal/GalNAc | Binding | 15302947 |
| Equine rhinitis A virus | Viral protein | α-mannose and α-glucose side chains of ConA-binding glycoproteins | Glycoproteins | Feline kidney(CRFK)/Equine fetal kidney(EFK)/Mouse(McCoy)/Rabbit kidney(RK-13) | Man/Glc | Binding | 15302947 |
| Escherichia coli | Shiga toxin (Stx2) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Vero cells | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 15292153 |
| Escherichia coli | Unknown | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Vero cells | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 15292153 |
| Helicobacter pylori | BabA (blood group antigen binding adhesin) | Blood group Lewis b (Leb) antigen | Oligosaccharides | Binding | 15273394 | ||
| Helicobacter pylori | BabA (blood group antigen binding adhesin) | Blood group H1 antigen (HSA) | Glycoproteins | Fuc(a1-2)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD | Binding | 15273394 | |
| Helicobacter pylori | BabA (blood group antigen binding adhesin) | Blood group B-Lewis b (BLeb) antigen | Oligosaccharides | Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc | Binding | 15273394 | |
| Helicobacter pylori | BabA (blood group antigen binding adhesin) | Blood group A-Lewis b (ALeb) antigen | Oligosaccharides | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc | Binding | 15273394 |
