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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▲ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Escherichia coli | (class III) | GL-III glycolipid | Glycolipids | Not Binding | 7721812 | ||
| Escherichia coli | P-fimbriae | GL-III glycolipid | Glycolipids | Not Binding | 7721812 | ||
| Escherichia coli | S-fimbriae | Sialyl galactoside units of cell surface glycoproteins | Glycoproteins | Vascular endothelial/epithelial cells of the choroid plexus, Ependyma cells lining the brain ventricles | NeuAc(a2-3)Gal(b1-4)Glc | Binding | 2893810 |
| Norovirus | Unknown | Sialylated type 2 chain conjugates (S-type 2-HSA) | Glycoproteins | Human serum albumin | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD | Binding | 19054801 |
| Norovirus | Unknown | Sialyl Lewis x (SLex-HSA) | Glycoproteins | Human serum albumin | NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD | Binding | 19054801 |
| Helicobacter pylori | Fibrillar hemmagglutinin | N-acetylneuraminyl-a(2-3)-galactopyranosyl sequence | Glycoproteins | Gastric epithelium, Mucus layer of the stomach | NeuAc(a2-3)Gal | Binding | 2459065 |
| Streptococcus gordonii | Ca2+-independent lectins | Hs antigen | Glycoproteins | NeuAc(a2-3)Gal(b1-4)Glc-HSA | Binding | 9393794 | |
| Adeno-associated virus | Unknown | Glycoproteins with α2,3 N-linked sialic acid | Glycoproteins | NeuAc(a2-3)Gal(b1-4)GlcNAc | Binding | 16940521 | |
| Mycoplasma pneumoniae | Unknown | Glycoproteins with terminal NeuAcα3Galβ4GlcNAc-sequences | Glycoproteins | NeuAc(a2-3)Gal(b1-4)GlcNAc | Binding | 15973004 | |
| Parvovirus | Unknown | O-linked alpha 2,3 neuraminic acid on glycophorin A (GPA) | Glycoproteins | Human erythrocytes | Binding | 15750863 | |
| Streptococcus gordonii | Adhesins | PMN (polymorphonuclear leukocytes) surface glycoproteins in the presence of sialic acid | Glycoproteins | Human peripheral blood buffy coat cells | Binding | 11035744 | |
| Rubulavirus | Unknown | N-linked sialylated glycoproteins | Glycoproteins | Pig neurons, glial cells | Binding | 16459111 | |
| Influenza virus | Unknown | Neuraminic acid-containing sialoglycoproteins | Glycoproteins | Binding | 15973004 | ||
| Clostridium difficile | Toxin A | α-Gal on Fab of IgA(κ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Clostridium difficile | Toxin A | α-Gal on Fab of IgM(λ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Norovirus | Unknown | Blood group B antigen (B-tri-HSA) | Glycoproteins | Human serum albumin | Gal(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Binding | 19054801 |
| Norovirus | Unknown | Blood group A antigen (A-tri-HSA) | Glycoproteins | Human serum albumin | GalNAc(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Binding | 19054801 |
| Norovirus | Unknown | Blood group A antigen (A-tri-HSA) | Glycoproteins | Saliva | GalNAc(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Binding | 18701592 |
| Clostridium difficile | Unknown | α-Gal on Fab of IgA(κ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Clostridium difficile | Unknown | α-Gal on Fab of IgM(λ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Escherichia coli | Type 1-fimbriae | Mannose-derived neoglycoproteins and dendrimers | Glycoproteins | Man | Binding | 16564136 | |
| Norovirus | Unknown | Blood group B antigen (B-tri-HSA) | Glycoproteins | Gal(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Binding | 18701592 | |
| Norovirus | Unknown | Blood group A antigen (A-tri-HSA) | Glycoproteins | GalNAc(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Binding | 18701592 | |
| Streptococcus suis | Unknown | Neoglycoproteins (containing Pk Antigen) | Glycoproteins | Gal(a1-4)Gal(b1-4)Glc | Binding | 8440715 | |
| Actinomyces naeslundii | Adhesins | PMN (polymorphonuclear leukocytes) surface glycoproteins | Glycoproteins | Human peripheral blood buffy coat cells | Binding | 11035744 |
