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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▼ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Polyoma virus | Capsid protein VP1 | Sialylated oligosaccharides | Oligosaccharides | Cell surface | NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc | Binding | 8805524 |
| Neisseria meningitidis | Unknown | Pentasaccharide | Oligosaccharides | Respiratory tract | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 16564136 |
| Adeno-associated virus | Unknown | NeuAcα2-3GalNAcβ1-4GlcNAc | Oligosaccharides | NeuAc(a2-3)GalNAc(b1-4)GlcNAc | Binding | 16940521 | |
| Mumps virus | MuV-HN | Glycans containing α2,3-linked sialic acid | Oligosaccharides | NeuAc(a2-3)Gal(b1-4)GlcNAc | Binding | 27671656 | |
| Mumps virus | MuV-HN | Glycans containing α2,3-linked sialic acid | Oligosaccharides | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-4]Man(a1-3)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc | Binding | 27671656 | |
| Escherichia coli | Type 1-fimbriae | Synthetic branched oligosaccharides: Man(a1-3)[Man(a1-6)]Man(a1-6)Man(a1-3)Man | Oligosaccharides | Patient with urinary tract infection | Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-3)]Man | Binding | 6138149 |
| Escherichia coli | Type 1-fimbriae | Synthetic branched oligosaccharides: Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-2)]Man(a1-3)Man | Oligosaccharides | Patient with urinary tract infection | Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-2)Man(a1-3)]Man | Binding | 6138149 |
| Escherichia coli | Type 1-fimbriae | unnamed ligand | Oligosaccharides | Urine | Man(a1-3)Man(a1-6)Man | Binding | 16564136 |
| Clostridium difficile | Toxin A | unnamed ligand | Oligosaccharides | Human colonic cells | GalNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 12507507 |
| Norovirus | Unknown | Blood group B antigen | Oligosaccharides | Saliva | Gal(a1-3)[Fuc(a1-2)]Gal | Binding | 18701592 |
| Norovirus | Unknown | Blood group A antigen | Oligosaccharides | Saliva | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc | Binding | 18701592 |
| Clostridium difficile | C-terminal domain of toxin A molecules | unnamed ligand | Oligosaccharides | Human colonic cells | GalNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 12507507 |
| Norovirus | Unknown | Blood group A antigen | Oligosaccharides | Human saliva | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc | Binding | 16707048 |
| Neisseria gonorrhoeae | Adhesins | unnamed ligand | Oligosaccharides | Mucos membranes of the genitourinary tract/rectum/oropharynx/conjunctiva | Gal(b1-4)GlcNAc(b1-4)Gal(b1-4)Glc | Binding | 2115881 |
| Neisseria gonorrhoeae | 18-kDa proteins | unnamed ligand | Oligosaccharides | Mucos membranes of the genitourinary tract/rectum/oropharynx/conjunctiva | Gal(b1-4)GlcNAc(b1-4)Gal(b1-4)Glc | Binding | 2115881 |
| Pseudomonas aeruginosa | PA-IIL | Blood group B antigen | Oligosaccharides | Gal(a1-3)[Fuc(a1-2)]Gal | Binding | 16762477 | |
| Pseudomonas aeruginosa | PA-IIL | Blood group A antigen | Oligosaccharides | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc | Binding | 16762477 | |
| Ralstonia solanacearum | RSL (30-kDa proteins) | Blood group B antigen | Oligosaccharides | Gal(a1-3)[Fuc(a1-2)]Gal | Binding | 16762477 | |
| Ralstonia solanacearum | RSL (30-kDa proteins) | Blood group A antigen | Oligosaccharides | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc | Binding | 16762477 | |
| Actinomyces viscosus | Type 2-fimbriae | unnamed ligand | Oligosaccharides | Gal(b1-4)Glc | Binding | 2885220 | |
| Actinomyces naeslundii | Type 2-fimbriae | unnamed ligand | Oligosaccharides | Gal(b1-4)Glc | Binding | 2885220 | |
| Escherichia coli | Verotoxin (1) | unnamed ligand | Oligosaccharides | Gal(a1-4)Gal(b1-4)Glc(b | Binding | 8574698 | |
| Norovirus | Capsid proteins | Blood group B antigen | Oligosaccharides | Gal(a1-3)[Fuc(a1-2)]Gal | Binding | 18809496 | |
| Norovirus | Capsid proteins | Blood group A antigen | Oligosaccharides | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc | Binding | 18809496 | |
| Norovirus | Capsid proteins | Blood group H1 antigen | Oligosaccharides | Fuc(a1-2)Gal(b1-3)GlcNAc | Binding | 18809496 |
