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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▲ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Escherichia coli | FimH | Collagen | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | Type 1-pili | CD48 | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | Type 1-pili | Uroplakins 1a and 1b containing a single N-linked carbohydrate of the high-mannose type | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | Type 1-pili | Collagen | Glycoproteins | Binding | 12010488 | ||
| Bordetella pertussis | Pertussis toxin | Fetuin | Glycoproteins | Binding | 1729677 | ||
| Poliovirus | Unknown | CD155 | Glycoproteins | Binding | 12663789 | ||
| Poliovirus | Unknown | Poliovirus receptors (PVRs) | Glycoproteins | Binding | 12663789 | ||
| Helicobacter pylori | Unknown | Mucin | Glycoproteins | Binding | 16088272 | ||
| Bordetella pertussis | PT (subunit S2 of B oligomer) | Fetuin | Glycoproteins | Binding | 1729677 | ||
| Influenza virus | Unknown | Bovine submaxillary mucin (BSM) | Glycoproteins | Binding | 1740131 | ||
| Neisseria meningitidis | 33-kDa proteins | factor H (fH) | Glycoproteins | Binding | 16751403 | ||
| Staphylococcus haemolyticus | 17-kDa HBP (Heparin-binding protein) | Basic fibroblast growth factor (bFGF) | Glycoproteins | Binding | 11393292 | ||
| Staphylococcus epidermidis | 17-kDa HBP (Heparin-binding protein) | Basic fibroblast growth factor (bFGF) | Glycoproteins | Binding | 11393292 | ||
| Borrelia burgdorferi | "DbpA, DbpB, Bgp" | Collagen (type I) | Glycoproteins | Binding | 16299269 | ||
| Bordetella pertussis | Pertactin | Integrins | Glycoproteins | Binding | 10341176 | ||
| Bordetella pertussis | Pertactin | Integrins | Glycoproteins | Binding | 12640357 | ||
| Norovirus | Unknown | Sialyl-dimeric Lewis x (SdiLex-HSA) | Glycoproteins | Human serum albumin | NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD | Binding | 19054801 |
| Clostridium difficile | Toxin A | β-Gal on Fab of IgG3(λ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Norovirus | Unknown | Blood group H1 antigen (HSA) | Glycoproteins | Human serum albumin | Fuc(a1-2)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD | Binding | 19054801 |
| Clostridium difficile | Unknown | β-Gal on Fab of IgG3(λ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Adenovirus | Fibre proteins | HSA glycoconjugates | Glycoproteins | Human corneal epithelial(HEC) cells | Binding | 15678425 | |
| Entamoeba histolytica | Transmembrane heavy subunit (Hgl; 170-kDa) disulfide linked to a GPI-anchored light subunit (Lgl; 31-to 35-kDa). | β-2 and β-7 integrins | Glycoproteins | Intestinal cells | Binding | 15322032 | |
| Sporothrix schenckii | Yeast cells and conidia | Fibronectin | Glycoproteins | Extracellular matrix (ECM) | Binding | 11598061 | |
| Paracoccidioides brasiliensis | Adhesins | Fibronectin | Glycoproteins | Human type II alveolar cells (A549) | Binding | 18083324 | |
| Streptococcus pyogenes | Protein F (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory endothelial cells | Binding | 10341176 |
