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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule ▲ | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Streptococcus pneumoniae | FcsSBP (fucose solute-binding protein) | Blood group B antigen | Oligosaccharides | Gal(a1-3)[Fuc(a1-2)]Gal | Binding | 19285508 | |
| Streptococcus pneumoniae | FcsSBP (fucose solute-binding protein) | Blood group A antigen | Oligosaccharides | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc | Binding | 19285508 | |
| Adenovirus | Fibre proteins | HSA glycoconjugates | Glycoproteins | Human corneal epithelial(HEC) cells | Binding | 15678425 | |
| Helicobacter pylori | Fibrillar hemmagglutinin | N-acetylneuraminyl-a(2-3)-galactopyranosyl sequence | Glycoproteins | Gastric epithelium, Mucus layer of the stomach | NeuAc(a2-3)Gal | Binding | 2459065 |
| Bordetella pertussis | Fim2 (H1/H2) | Heparin | Glycosaminoglycans | ECM | Binding | 11348687 | |
| Escherichia coli | Fim2 (H1/H2) | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Streptococcus parasanguinis | FimA (Lary family) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus parasanguinis | FimA (Lral family); localized to the tip of peritrichous surface fimbria | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Escherichia coli | FimCH-chaperone-adhesin complex | D-Mannose | Monosaccharides | Bladder epithelium | Man | Binding | 12010488 |
| Escherichia coli | FimD | unnamed ligand | Oligosaccharides | Gal(a1-4)Gal | Binding | 12628483 | |
| Bordetella pertussis | FimD | VLA-5 (very late activation antigen 5) | Glycoproteins | Monocytes | Binding | 11348687 | |
| Escherichia coli | FimG/FimH | Mannose oligosaccharides | Oligosaccharides | Man | Binding | 9973330 | |
| Escherichia coli | FimH | Mannose oligosaccharides | Oligosaccharides | Eukaryotic cells | Man | Binding | 12640357 |
| Escherichia coli | FimH | Mannose oligosaccharides | Oligosaccharides | Man | Binding | 10341176 | |
| Escherichia coli | FimH | Mannotriose | Oligosaccharides | Man(a1-3)[Man(a1-6)]Man | Binding | 12010488 | |
| Escherichia coli | FimH | CD48 | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | FimH | Uroplakins 1a and 1b containing a single N-linked carbohydrate of the high-mannose type | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | FimH | Collagen | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | FimH | Tamm-Horsfall protein (THP) | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | FimH | Fibronectin | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | FimH | Laminin | Glycoproteins | Binding | 12010488 | ||
| Moraxella catarrhalis | Fimbriae | GM2(NeuAc) | Monosialoglycosphingolipids | Human pharyngeal epithelial cells | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 12137200 |
| Moraxella catarrhalis | Fimbriae | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Other than pharyngeal epithelial cells | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 12137200 |
| Neisseria gonorrhoeae | Fimbriae | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 10816509 | |
| Pseudomonas aeruginosa | Fimbriae | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 10816509 |
