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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▼ | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Escherichia coli | PrsG (class III) | Glucosylceramide | Monoglycosylceramides | Colonic adenocarcinoma | Glc(b1-1)Cer | Not Binding | 9673272 |
| Escherichia coli | PapG (class I) | Glucosylceramide | Monoglycosylceramides | Colonic adenocarcinoma | Glc(b1-1)Cer | Not Binding | 9673272 |
| Escherichia coli | P-fimbriae | Glucosylceramide | Monoglycosylceramides | Colonic adenocarcinoma | Glc(b1-1)Cer | Not Binding | 9673272 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | Glucosylceramide | Monoglycosylceramides | Various sources | Glc(b1-1)Cer | Not Binding | 9499377 |
| Escherichia coli | PapG (class II) | Glucosylceramide | Monoglycosylceramides | Colonic adenocarcinoma | Glc(b1-1)Cer | Not Binding | 9673272 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Glucosylceramide | Monoglycosylceramides | Gonorrhoeae patients | Glc(b1-1)Cer | Not Binding | 2468365 |
| Actinomyces viscosus | Unknown | Glucosylceramide | Monoglycosylceramides | Most tissues | Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces naeslundii | Unknown | Glucosylceramide | Monoglycosylceramides | Most tissues | Glc(b1-1)Cer | Not Binding | 2358461 |
| Escherichia coli | PsaA/B (pH-6 antigen) | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Not Binding | 9712817 | |
| Rotavirus | Unknown | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Not Binding | 11160731 | |
| Yersinia pestis | PsaA/B (pH-6 antigen) | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Not Binding | 9712817 | |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Not Binding | 2468365 | |
| Cytomegalovirus | Unknown | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Not Binding | 9780061 | |
| Propionibacterium freudenreichii | Unknown | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Not Binding | 2435422 | |
| Propionibacterium granulosum | Unknown | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Not Binding | 2435422 | |
| Vibrio cholerae | MSHA (mannose/glucose-specific hemagglutinin) | Glucose | Monosaccharides | Patient with acute watery diarrhea | Glc | Binding | 10219594 |
| Treponema pallidum | Tp38 (TpMglB-2) lipoproteins | Glucose | Monosaccharides | Glc | Binding | 15060032 | |
| Clostridium botulinum | Botulinum neurotoxin (16S) | Glucose | Monosaccharides | Intestinal epithelial cells (T84) | Glc | Not Binding | 17156748 |
| Clostridium botulinum | HA | Glucose | Monosaccharides | Intestinal epithelial cells (T84) | Glc | Not Binding | 17156748 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | GgO3 (de-N- acylated) | Oligoglycosylceramides | Guinea pig erythrocytes | GalNH2(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
| Rotavirus | Unknown | GD2(NeuGc) | Disialoglycosphingolipids | GalNAc(b1-4)[NeuGc(a2-8)NeuGc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11160731 | |
| Escherichia coli | K99 | GM2(NeuGc) | Monosialoglycosphingolipids | GalNAc(b1-4)[NeuGc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7849044 | |
| Rotavirus | Unknown | GM2(NeuGc) | Monosialoglycosphingolipids | GalNAc(b1-4)[NeuGc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 11160731 | |
| Clostridium tetani | Tetanus neurotoxin | GD2 | Disialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 | |
| Escherichia coli | Heat-labile enterotoxin (type II(LT-Iia)) | GD2 | Disialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3290106 |
