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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name ▼ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Helicobacter pylori | Unknown | PGCs (polyglycosyl ceramides) | Glycosphingolipids | Human erythrocytes, Human leukocytes, Human placenta | Binding | 9169796 | |
| Helicobacter pylori | Unknown | PGCs (polyglycosyl ceramides) | Glycosphingolipids | Rat small intestine, Wild boar intestine, Monkey intestine | Binding | 9169796 | |
| Helicobacter pylori | Unknown | PGCs (polyglycosyl ceramides) | Glycosphingolipids | Binding | 12628483 | ||
| Influenza virus | Unknown | PGCs (polyglycosyl ceramides) | Glycosphingolipids | Binding | 12628483 | ||
| Streptococcus suis | Adhesins | P1 antigen (GSL) | Glycosphingolipids | Gal(a1-4)Gal | Binding | 7961660 | |
| Pseudomonas aeruginosa | PA-IIL | P-nitrophenyl-alpha-L-fucose | Monosaccharides | Binding | 10967261 | ||
| Haemophilus influenzae | HMW1 | Oligosaccharides rich in sialic acid | Oligosaccharides | Human epithelial cells | Binding | 12640357 | |
| Haemophilus influenzae | HMW2 | Oligosaccharides rich in sialic acid | Oligosaccharides | Human epithelial cells | Binding | 12640357 | |
| Haemophilus influenzae | Hia | Oligosaccharides rich in sialic acid | Oligosaccharides | Human conjunctival cells (respiratory tract) | Binding | 12640357 | |
| Lassa virus | Glycoprotein (GP) | O-mannosyl glycans on alpha-dystroglycan (DG) | O-glycans | Fibroblasts, Epithelial cells, Endothelial cells, Hepatocytes | Binding | 17360738 | |
| Lymphocytic choriomeningitis virus | Glycoprotein (GP) | O-mannosyl glycans on alpha-dystroglycan (DG) | O-glycans | Fibroblasts, Epithelial cells, Endothelial cells, Hepatocytes | Binding | 17360738 | |
| New world arenavirus | Glycoprotein (GP) | O-mannosyl glycans on alpha-dystroglycan (DG) | O-glycans | Binding | 17360738 | ||
| Parvovirus | Unknown | O-linked alpha 2,3 neuraminic acid on glycophorin A (GPA) | Glycoproteins | Human erythrocytes | Binding | 15750863 | |
| Plasmodium falciparum | Unknown | Neuraminidase-insensitive, trypsin sensitive carbohydrate ligand | Glycoconjugates | Molecules on the erythrocyte membrane (other than glycophorins A and B) | Binding | 3308959 | |
| Influenza virus | Unknown | Neuraminic acid-containing sialoglycosphingolipids | Sialoglycosphingolipids | Binding | 15973004 | ||
| Influenza virus | Unknown | Neuraminic acid-containing sialoglycoproteins | Glycoproteins | Binding | 15973004 | ||
| Influenza virus | Unknown | Neuraminic acid | Monosaccharides | Binding | 8574698 | ||
| Lactobacillus johnsonii | Unknown | NeuGc3-nLc6Cer | Sialoglycosphingolipids | Rabbit thymus | NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11087711 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | NeuGc3-nLc6Cer | Sialoglycosphingolipids | Rabbit thymus | NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 9228091 |
| Rotavirus | Unknown | NeuGc3-nLc6Cer | Sialoglycosphingolipids | NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11160731 | |
| Mycoplasma pneumoniae | Unknown | NeuGc3-nLc6Cer | Sialoglycosphingolipids | Human colon adenocarcinoma cells (WiDr ) | NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2470753 |
| Influenza virus | Unknown | NeuGc3-nLc6Cer | Sialoglycosphingolipids | NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7870741 | |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | NeuGc3-Lc4Cer (Sialyl lactotetraosylceramide) | Sialoglycosphingolipids | Rabbit thymus | NeuGc(a2-3)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Escherichia coli | S-fimbriae | NeuAcα3Galβ-containing glycoproteins | Glycoproteins | Lumenal surfaces of the vascular endothelium in the neonatal rat brain | NeuAc(a2-3)Gal(b | Binding | 15973004 |
| Escherichia coli | SfaS | NeuAcα3Galβ-containing glycoproteins | Glycoproteins | Lumenal surfaces of the vascular endothelium in the neonatal rat brain | NeuAc(a2-3)Gal(b | Binding | 15973004 |
