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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source ▼ | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | GM3(NeuAc) | Monosialoglycosphingolipids | Human granulocytes | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Sialyl-3-Paragloboside (S-3-PG; α2,3-sialylparagloboside) | Monosialoglycosphingolipids | Human granulocytes | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Helicobacter pylori | Adhesins | GM3(NeuAc) | Monosialoglycosphingolipids | Human gastric mucosa | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2037054 |
| Helicobacter pylori | Adhesins | Sulfatide (CSE) | Sulfoglycosphingolipids | Human gastric mucosa | HSO3(-3)Gal(b1-1)Cer | Binding | 2037054 |
| Helicobacter pylori | BabA (blood group antigen binding adhesin) | Fucosylated Lewis b (Leb) histoblood group antigens | Oligosaccharides | Human gastric epithelium | Binding | 9430586 | |
| Propionibacterium freudenreichii | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human erythrocytes, Whole dog small intestine | Gal(b1-4)Glc(b1-1)Cer | Binding | 2452754 |
| Shigella dysenteriae | B subunit | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Human erythrocytes, Rat small intestine | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3543013 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Human erythrocytes, Rabbit intestine | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
| Escherichia coli | Adhesins | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Human erythrocytes, Human uroepithelial cells | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7037645 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | NeuAc3-nLc6Cer (Sialyl neolactohexaosylceramide) | Sialoglycosphingolipids | Human erythrocytes, Human placenta | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 9228091 |
| Helicobacter pylori | Unknown | PGCs (polyglycosyl ceramides) | Glycosphingolipids | Human erythrocytes, Human leukocytes, Human placenta | Binding | 9169796 | |
| Parvovirus | Unknown | O-linked alpha 2,3 neuraminic acid on glycophorin A (GPA) | Glycoproteins | Human erythrocytes | Binding | 15750863 | |
| Escherichia coli | PrsG (class III) | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Human erythrocytes | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | PapG (class I) | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Human erythrocytes | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | P-fimbriae | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Human erythrocytes | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | PapG (class II) | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Human erythrocytes | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Lactobacillus johnsonii | Unknown | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Human erythrocytes | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11087711 |
| Shigella dysenteriae | B subunit | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Human erythrocytes | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3543013 |
| Actinomyces naeslundii | Unknown | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Human erythrocytes | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Actinomyces viscosus | Unknown | GM3(NeuAc) | Monosialoglycosphingolipids | Human erythrocytes | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces naeslundii | Unknown | GM3(NeuAc) | Monosialoglycosphingolipids | Human erythrocytes | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | unnamed ligand | Sialoglycosphingolipids | Human erythrocytes | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 9228091 |
| Escherichia coli | PapG (class I) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Human erythrocytes | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | P-fimbriae | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Human erythrocytes | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Human erythrocytes | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
