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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▲ | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Gonorrhoeae patients | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Human meconium | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Shigella dysenteriae | B subunit | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Human meconium | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Vibrio cholerae | Cholera toxin | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Escherichia coli | Heat-labile enterotoxin | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Vibrio cholerae | Unknown | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Escherichia coli | K88ab | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11953368 | |
| Escherichia coli | Unknown | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Propionibacterium freudenreichii | Unknown | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Pseudomonas aeruginosa | PA-IIL | Lewis a (Lea) (GSL) | Glycosphingolipids | Airways | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 18809496 |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | Lewis a (Lea) (GSL) | Glycosphingolipids | Human skin | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Pseudomonas aeruginosa | PA-IIL | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 16762477 | |
| Norovirus | Unknown | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 18701592 | |
| Propionibacterium granulosum | Unknown | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
| Escherichia coli | F1C | Lewis a (Lea) (GSL) | Glycosphingolipids | Human meconium | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Lewis a (Lea) (GSL) | Glycosphingolipids | Gonorrhoeae patients | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Lactobacillus johnsonii | Unknown | Lewis a (Lea) (GSL) | Glycosphingolipids | Human small intestine | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11087711 |
| Helicobacter mustelae | Lectin-hemagglutinin adhesins | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 | |
| Helicobacter bilis | Lectin-hemagglutinin adhesins | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 | |
| Helicobacter pylori | Lectin-hemagglutinin adhesins | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 | |
| Escherichia coli | K88ab/K88ac/K88ad | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11953368 | |
| Helicobacter hepaticus | Lectin-hemagglutinin adhesins | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 | |
| Helicobacter felis | Lectin-hemagglutinin adhesins | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 | |
| Norovirus | Unknown | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 18701592 | |
| Helicobacter canis | Lectin-hemagglutinin adhesins | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 |
