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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species ▲ | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Escherichia coli | PapG | Globo-series GSL | Glycosphingolipids | Uroepithelial cells, Erythrocytes | Gal(a1-4)Gal | Binding | 9973330 |
| Escherichia coli | PapG (class I) G adhesins | Gal alpha 1-4 Gal-containing isoreceptors | Glycosphingolipids | Pyelonephritis patients | Gal(a1-4)Gal | Binding | |
| Escherichia coli | F1C | Glucosylceramide (t18:0-h18:0) | Monoglycosylceramides | Rat intestine | Glc(b1-1)Cer | Binding | 11877427 |
| Escherichia coli | PapG (class I) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Human erythrocytes | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | CS3 (coli surface 3)-fimbriae | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Intestinal epithelium, Rabbit intestine | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7822033 |
| Escherichia coli | P-fimbriae | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Human erythrocytes | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | Shiga-like toxin (Stx1) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | GI/kidney | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 18809496 |
| Escherichia coli | Shiga toxin (Stx2) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Vero cells | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 15292153 |
| Escherichia coli | PapG (class II) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Human erythrocytes | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | F1C | H5 type 2 pentaglycosylceramide (neolacto-series) | Oligoglycosylceramides | Human erythrocytes | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Escherichia coli | F1C | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Guinea pig erythrocytes | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Escherichia coli | F1C | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Human neutrophils | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Escherichia coli | F1C | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Human erythrocytes | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Escherichia coli | F1C | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) (t18:0-h20:0-h24:0) | Oligoglycosylceramides | Human kidney tissues | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11877427 |
| Escherichia coli | F1C | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Human meconium | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11877427 |
| Escherichia coli | Unknown | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Vero cells | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 15292153 |
| Escherichia coli | Unknown | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | GI/kidney | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 18809496 |
| Escherichia coli | Type 1-fimbriae | Synthetic branched oligosaccharides: Man(a1-3)[Man(a1-6)]Man(a1-6)Man(a1-3)Man | Oligosaccharides | Patient with urinary tract infection | Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-3)]Man | Binding | 6138149 |
| Escherichia coli | Type 1-fimbriae | Synthetic branched oligosaccharides: Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-2)]Man(a1-3)Man | Oligosaccharides | Patient with urinary tract infection | Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-2)Man(a1-3)]Man | Binding | 6138149 |
| Escherichia coli | Type 1-fimbriae | unnamed ligand | Oligosaccharides | Urine | Man(a1-3)Man(a1-6)Man | Binding | 16564136 |
| Escherichia coli | SfaA | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 | |
| Escherichia coli | PsaA/B (pH-6 antigen) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 9712817 | |
| Escherichia coli | S-fimbriae | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 | |
| Escherichia coli | P-fimbriae | Gb2 (Galabiosylceramide) | Diosylceramides | Gal(a1-4)Gal(b1-1)Cer | Binding | 7721812 | |
| Escherichia coli | F1C | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 10816509 |
