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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▲ | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Legionella pneumophila | Adhesins | unnamed ligand | Oligosaccharides | Human epithelial cells (respiratory tract) | Gal(b1-4)GlcNAc | Binding | 14687561 |
| Fusobacterium nucleatum | Lectin-like proteins (adhesin) | unnamed ligand | Oligosaccharides | Gal(b1-4)GlcNAc | Binding | 1894623 | |
| Entamoeba histolytica | Unknown | unnamed ligand | Oligosaccharides | Gal(b1-4)GlcNAc | Binding | 12628483 | |
| Staphylococcus saprophyticus | Unknown | unnamed ligand | Oligosaccharides | Gal(b1-4)GlcNAc | Binding | 2885220 | |
| Streptococcus pneumoniae | Unknown | unnamed ligand | Oligosaccharides | Chinchilla tubotympanum | Gal(b1-4)GlcNAc(b1-3)Gal(b | Binding | 1298868 |
| Streptococcus pneumoniae | Unknown | Tetrasaccharides | Oligosaccharides | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc | Binding | 16564136 | |
| Streptococcus pneumoniae | CBPs (choline-binding proteins) | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Cytokine-activated cells | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12640357 |
| Streptococcus pneumoniae | Unknown | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Chinchilla tracheal epithelium | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 10090858 |
| Neisseria gonorrhoeae | Adhesins | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Mucos membranes of the genitourinary tract/rectum/oropharynx/conjunctiva | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2115881 |
| Streptococcus pneumoniae | CbpA; SpsA; PbcA; PspC (CBPs) | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Cytokine activated epithelial and endothelial cells | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 10341176 |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Human skin | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Actinomyces viscosus | Unknown | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Dog small intestine | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Mycoplasma pneumoniae | Unknown | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Human colon adenocarcinoma cells (WiDr ) | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2470753 |
| Lactobacillus johnsonii | Unknown | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Human erythrocytes | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11087711 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Human granulocytes | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 9228091 |
| Lactobacillus casei | Unknown | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Intestinal tract | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 8912650 |
| Actinomyces naeslundii | Unknown | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Dog small intestine | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Escherichia coli | K88ab/K88ac/K88ad | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11953368 | |
| Streptococcus pneumoniae | Adhesins | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2115881 | |
| Escherichia coli | Heat-labile enterotoxin | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 8574698 | |
| Escherichia coli | Heat-labile enterotoxin | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Escherichia coli | Heat-labile enterotoxin | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 7527546 | |
| Rotavirus | Unknown | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11160731 | |
| Pseudomonas aeruginosa | Adhesins | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2115881 | |
| Haemophilus influenzae | Adhesins | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2115881 |
