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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID ▲ |
|---|---|---|---|---|---|---|---|
| Influenza virus | Unknown | NeuAc6-Lc4Cer (Sialyl lactotetraosylceramide) | Sialoglycosphingolipids | NeuAc(a2-6)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7870741 | |
| Influenza virus | Unknown | NeuGc3-nLc6Cer | Sialoglycosphingolipids | NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7870741 | |
| Influenza virus | Unknown | GM3(Neu4Ac5Gc) | Monosialoglycosphingolipids | Ac(-4)Neu5Gc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7870741 | |
| Influenza virus | Unknown | NeuAc3-nLc6Cer (Sialyl neolactohexaosylceramide) | Sialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 7870741 | |
| Influenza virus | Unknown | NeuAc3-nLc6Cer (Sialyl neolactohexaosylceramide) | Sialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7870741 | |
| Escherichia coli | Fimbrial lectin (adhesin) protein GafD (25-kDa) | N-Acetylglucosamine | Monosaccharides | GlcNAc | Binding | 7883703 | |
| Streptococcus suis | Adhesins | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Erythrocytes | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7961660 |
| Streptococcus suis | Adhesins | P1 antigen (GSL) | Glycosphingolipids | Gal(a1-4)Gal | Binding | 7961660 | |
| Streptococcus suis | Adhesins | Gb2 (Galabiosylceramide) | Diosylceramides | Gal(a1-4)Gal(b1-1)Cer | Binding | 7961660 | |
| Streptococcus suis | Adhesins | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Erythrocytes | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7961660 |
| Influenza virus | Residues 226 (glutamine) and 228 (glycine) | Sialic acid linked to α2,3Galβ1,3GalNAc | Oligosaccharides | Avian/equine isolates | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 7975212 |
| Influenza virus | Residues 226 (leucine) and 228 (serine) | Sialic acid α2,6Galβ1,4GalNAc | Oligosaccharides | Human isolates | NeuAc(a2-6)Gal(b1-4)GalNAc | Binding | 7975212 |
| Candida albicans | 66-kDa subunit | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Human buccal epihelial cells (BECs) | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8005674 |
| Candida albicans | "Extracellular polymeric material, acid proteinase, chitin" | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Human buccal epihelial cells (BECs) | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8005674 |
| Candida albicans | 66-kDa subunit | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Human buccal epihelial cells (BECs) | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8005674 |
| Candida albicans | "Extracellular polymeric material, acid proteinase, chitin" | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Human buccal epihelial cells (BECs) | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8005674 |
| Helicobacter pylori | Adhesins | Blood group Lewis b (Leb) antigen | Oligosaccharides | Binding | 8018146 | ||
| Escherichia coli | S-fimbriae (SfaA) | Seminolipid (Sulfogalactosylglycerolipid) | Glycolipids | Brain endothelial cells | Gal(3SO4)(b1-1)-alkylacylglycerol | Binding | 8098039 |
| Escherichia coli | S-fimbriae (SfaA) | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Brain endothelial cells | Gal(b1-1)Cer | Binding | 8098039 |
| Escherichia coli | S-fimbriae (SfaA) | Galactosyl sulfatide | Sulfoglycosphingolipids | Brain endothelial cells | Gal(3SO4)(b1-1)Cer | Binding | 8098039 |
| Escherichia coli | S-fimbriae (SfaA) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Brain endothelial cells | Gal(b1-4)Glc(b1-1)Cer | Binding | 8098039 |
| Streptococcus suis | Unknown | Neoglycoproteins (containing Pk Antigen) | Glycoproteins | Gal(a1-4)Gal(b1-4)Glc | Binding | 8440715 | |
| Escherichia coli | P adhesin (PapG AD110 type) | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8440715 | |
| Escherichia coli | P adhesin (PapG AD110 type) | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8440715 | |
| Streptococcus suis | Unknown | Neoglycoproteins (containing P1 Antigen) | Glycoproteins | Gal(a1-4)Gal(b1-4)GlcNAc | Binding | 8440715 |
