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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID ▲ |
|---|---|---|---|---|---|---|---|
| Streptococcus suis | Unknown | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8440715 | |
| Human immunodeficiency virus | gp120 | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Human colonic epithelial cell lines (HT-29/HT-29-A7/HT-29-D4) | Gal(b1-1)Cer | Binding | 8464878 |
| Bordetella pertussis | CRD (carbohydrate recognition domain) of Fha (Filamentous Hemagglutinin) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Respiratory ciliated cells, Alveolar macrophages | Gal(b1-4)Glc(b1-1)Cer | Binding | 8514379 |
| Escherichia coli | 20K-fimbriae | GlcNAc sequence | Saccharides | Human colon carcinoma Caco-2 cell line | GlcNAc | Binding | 8557360 |
| Polyoma virus | Unknown | unnamed ligand | Oligosaccharides | Murine small plaque | NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc | Binding | 8574698 |
| Vibrio cholerae | Cholera toxin | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 8574698 | |
| Escherichia coli | Heat-labile enterotoxin | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 8574698 | |
| Vibrio cholerae | Unknown | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 8574698 | |
| Escherichia coli | Unknown | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 8574698 | |
| Vibrio cholerae | Cholera toxin | GM1 | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 8574698 | |
| Escherichia coli | Heat-labile enterotoxin | GM1 | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 8574698 | |
| Escherichia coli | Heat-labile enterotoxin | GM2(NeuAc) | Monosialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 8574698 | |
| Vibrio cholerae | Unknown | GM1 | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 8574698 | |
| Escherichia coli | Unknown | GM1 | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 8574698 | |
| Escherichia coli | Unknown | GM2(NeuAc) | Monosialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 8574698 | |
| Bordetella pertussis | FHA (filamentous hemagglutinin) | Sulfatide (CSE) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-1)Cer | Binding | 8574698 | |
| Plasmodium falciparum | Unknown | Sulfatide (CSE) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-1)Cer | Binding | 8574698 | |
| Bordetella pertussis | FHA (filamentous hemagglutinin) | Heparan sulfate | Glycosaminoglycans | Binding | 8574698 | ||
| Bordetella pertussis | FHA (filamentous hemagglutinin) | Heparan sulfate | Glycosaminoglycans | Binding | 8574698 | ||
| Bordetella pertussis | FHA (filamentous hemagglutinin) | Heparan sulfate | Glycosaminoglycans | Binding | 8574698 | ||
| Bordetella pertussis | FHA (filamentous hemagglutinin) | Heparan sulfate | Glycosaminoglycans | Binding | 8574698 | ||
| Escherichia coli | P-fimbriae | Gal alpha 1-4 Gal-containing glicolipids | Glycolipids | Pyelonephritis patients | Gal(a1-4)Gal | Binding | 8574698 |
| Escherichia coli | PapG | Gal alpha 1-4 Gal-containing glicolipids | Glycolipids | Pyelonephritis patients | Gal(a1-4)Gal | Binding | 8574698 |
| Pseudomonas aeruginosa | PA-I | Galactose | Monosaccharides | Gal | Binding | 8574698 | |
| Helicobacter pylori | Unknown | Fucose | Monosaccharides | Fuc | Binding | 8574698 |
