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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID ▼ |
|---|---|---|---|---|---|---|---|
| Influenza virus | Hemagglutinin (HA) | GT1b | Trisialoglycosphingolipids | Various human tissues (leukocytes/erythrocytes/small intestine/stomach/meconium/colon/pancreas) | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 11030743 |
| Influenza virus | SNA lectins | Minor NeuAcα6-containing molecules | Glycoconjugates | Human leukocytes | Binding | 11030743 | |
| Influenza virus | Hemagglutinin (HA) | Gangliosides | Glycosphingolipids | Human leukocytes | Binding | 11030743 | |
| Helicobacter pylori | Unknown | Salivary glycoprotein (gp340) | Glycoproteins | Human stomach associated with gastritis and peptic ulcer disease | Binding | 11007786 | |
| Streptococcus agalactiae | Unknown | Salivary glycoprotein (gp340) | Glycoproteins | Neonatal meningitis | Binding | 11007786 | |
| Streptococcus mutans | Unknown | Salivary glycoprotein (gp340) | Glycoproteins | Dental plaque (caries-associated) | Binding | 11007786 | |
| Escherichia coli | AC/I-fimbriae (S-fimbrial family) | unknown carbohydrate ligand | Saccharides | Septicemic avian epithelial cells | Binding | 10992500 | |
| Pseudomonas aeruginosa | PA-IL | Melibiose | Disaccharides | Gal(a1-6)Glc | Binding | 10967261 | |
| Pseudomonas aeruginosa | PA-IIL | Fucosylamine | Monosaccharides | Fuc | Binding | 10967261 | |
| Pseudomonas aeruginosa | PA-IIL | D-Mannose | Monosaccharides | Man | Binding | 10967261 | |
| Pseudomonas aeruginosa | PA-IIL | L-Fucose | Monosaccharides | Fuc | Binding | 10967261 | |
| Pseudomonas aeruginosa | PA-IL | N-Acetylgalactosamine | Monosaccharides | GalNAc | Binding | 10967261 | |
| Pseudomonas aeruginosa | PA-IL | Galactose | Monosaccharides | Gal | Binding | 10967261 | |
| Pseudomonas aeruginosa | PA-IIL | P-nitrophenyl-alpha-L-fucose | Monosaccharides | Binding | 10967261 | ||
| Pseudomonas aeruginosa | PA-IL | Methyl-β-Gal | Monosaccharides | Binding | 10967261 | ||
| Pseudomonas aeruginosa | PA-IL | Methyl-α-Gal | Monosaccharides | Binding | 10967261 | ||
| Pseudomonas aeruginosa | PA-IIL | L-Galactose | Monosaccharides | Gal | Binding | 10967261 | |
| Escherichia coli | F1C | Galactosylceramide (nonhydroxylated fatty acids) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 10816509 | |
| Neisseria gonorrhoeae | Fimbriae | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 10816509 | |
| Pseudomonas aeruginosa | Fimbriae | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 10816509 | |
| Escherichia coli | F1C | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 10816509 | |
| Escherichia coli | F1C | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 10816509 | |
| Neisseria gonorrhoeae | 18-kDa proteins | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 10816509 | |
| Escherichia coli | F1C | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 10816509 | |
| Escherichia coli | F1C | GD2 | Disialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 10816509 |
