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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name ▲ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Helicobacter pylori | Unknown | GT1b | Trisialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9169796 | |
| Clostridium botulinum | Botulinum neurotoxin | GT1b (complex with synaptotagmin II) | Trisialoglycosphingolipids | Presynaptic membrane of neuromuscular junction | Binding | 7527117 | |
| Clostridium botulinum | BoNT/B | GT1b (complex with synaptotagmin II) | Trisialoglycosphingolipids | Presynaptic membrane of neuromuscular junction | Binding | 7527117 | |
| Clostridium tetani | Tetanus toxin (Hc fragment) | GT1b analog | Trisialoglycosphingolipids | Synapse | Binding | 18809496 | |
| Clostridium tetani | Unknown | GT1b analog | Trisialoglycosphingolipids | Synapse | Binding | 18809496 | |
| Influenza virus | Unknown | GT3 | Trisialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7870741 | |
| Escherichia coli | P-fimbriae | Gal alpha 1-4 Gal-containing glicolipids | Glycolipids | Pyelonephritis patients | Gal(a1-4)Gal | Binding | 8574698 |
| Escherichia coli | PapG | Gal alpha 1-4 Gal-containing glicolipids | Glycolipids | Pyelonephritis patients | Gal(a1-4)Gal | Binding | 8574698 |
| Escherichia coli | PrsG | Gal alpha 1-4 Gal-containing glicolipids | Glycolipids | Gal(a1-4)Gal | Binding | 12640357 | |
| Escherichia coli | PapG | Gal alpha 1-4 Gal-containing glicolipids | Glycolipids | Gal(a1-4)Gal | Binding | 12640357 | |
| Escherichia coli | PapG (class II) G adhesins | Gal alpha 1-4 Gal-containing isoreceptors | Glycosphingolipids | Patient with septic infection or pyelonephritis | Gal(a1-4)Gal | Binding | |
| Escherichia coli | P-fimbriae | Gal alpha 1-4 Gal-containing isoreceptors | Glycosphingolipids | Patient with septic infection or pyelonephritis | Gal(a1-4)Gal | Binding | |
| Escherichia coli | P-fimbriae | Gal alpha 1-4 Gal-containing isoreceptors | Glycosphingolipids | Pyelonephritis patients | Gal(a1-4)Gal | Binding | |
| Escherichia coli | PapG (class I) G adhesins | Gal alpha 1-4 Gal-containing isoreceptors | Glycosphingolipids | Pyelonephritis patients | Gal(a1-4)Gal | Binding | |
| Escherichia coli | PapG | Gal(a1-4)Gal in globo-series of glycolipids | Glycosphingolipids | Gal(a1-4)Gal | Binding | 10341176 | |
| Escherichia coli | PrsG | Gal(a1-4)Gal in globo-series of glycolipids | Glycosphingolipids | Gal(a1-4)Gal | Binding | 10341176 | |
| Shigella dysenteriae | B subunit | Gal-Gb3 | Oligoglycosylceramides | Rat small intestine | Gal(a1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3543013 |
| Shigella dysenteriae | Shiga toxin | Gal-Gb3 | Oligoglycosylceramides | Gal(a1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
| Escherichia coli | Unknown | Gal-Gb3 | Oligoglycosylceramides | Gal(a1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
| Shigella dysenteriae | Unknown | Gal-Gb3 | Oligoglycosylceramides | Gal(a1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
| Shigella dysenteriae | B subunit | Gal-nLc4Cer; P1 antigen (GSL) | Oligoglycosylceramides | Human type B erythrocytes | Gal(a1-4)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 3519828 |
| Shigella dysenteriae | B subunit | Gal-nLc4Cer; P1 antigen (GSL) | Oligoglycosylceramides | Human erythrocytes | Gal(a1-4)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 3543013 |
| Shigella dysenteriae | Shiga toxin | Gal-nLc4Cer; P1 antigen (GSL) | Oligoglycosylceramides | Gal(a1-4)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
| Escherichia coli | Unknown | Gal-nLc4Cer; P1 antigen (GSL) | Oligoglycosylceramides | Gal(a1-4)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
| Shigella dysenteriae | Unknown | Gal-nLc4Cer; P1 antigen (GSL) | Oligoglycosylceramides | Gal(a1-4)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 |
